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Food safety is one of the hot issues in all over the world. It is related to national economy and people's livelihood. In recent years, food safety accidents occur in China frequently, so an effective food safety network public opinion early warning model is necessary and imperative. Therefore, the model of Back Propagation neural network based on Analytic Hierarchy Process (AHP-BP) is proposed. The...
The integrin α v β 6 is an emergent biomarker for non-small cell lung cancer (NSCLC) as well as other carcinomas. We previously developed a tetrameric peptide, referred to as H2009.1, which binds α v β 6 and displays minimal affinity for other RGD-binding integrins. Here we report the use of this peptide to actively deliver paclitaxel to α v β 6 -positive...
In our previous paper it was shown that the two C-terminal Gln residues of a C-terminal 15-residue fragment, Mel(12–26) (GLPALISWIKRKRQQ-NH 2 ), of melittin and a series of individual substituted analogues might not involved in the interaction with bacterial membranes. In this paper, peptides with one and two Gln residues deletion, respectively, Mel(12–25) and Mel(12–24), were synthesized...
Residues 1–9 of M(12–26) (GLPALISWIKRKRQQ-NH2), the C-terminal 15-residue segment of melittin, were substituted individually to change the hydropathicities in these positions. Antimicrobial and hemolytic activities of these peptides were determined. The results showed increased antimicrobial activities with increased hydrophobicities at almost all the positions studied. The effects at positions 2,...
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