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2,5-Di(tert-butyl)-1,4-benzohydroquinone has been shown to inhibit the Ca 2+ , Mg 2+ -ATPase of sarcoplasmic reticulum with an affinity of 0.4 μM. It has been shown to shift the E2-E1 equilibrium for the ATPase towards E2, as shown previously for the inhibitor thapsigargin. The shift towards E2 results in a decrease in affinity for Ca 2+ , as also observed for...
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