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Recent reports have suggested role for epidermal growth factor receptor (EGFR) in asthma and skin inflammation. Integrin(s) are known to be necessary for the transactivation of EGFR. The roles of EGFR and integrin(s) in allergic inflammation were investigated. Antigen stimulation induced activation of EGFR and interaction between EGFR and integrin α 5 in Rat Basophilic Leukemia (RBL2H3) cells...
Cancer associated gene (CAGE) regulates expression of epithelial-mesenchymal transition (EMT)-related proteins through extracellular regulated kinase (ERK), Akt and nuclear factor κB (NF-kB) in mouse B16F10 melanoma cells. Snail, a EMT-related protein, mediates the effect of CAGE on the induction of matrix metalloproteinase-2 (MMP-2) and cancer cell motility. C-Flice inhibitory protein mediates the...
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