Search results for: Wei-Che Lin

Items from 1 to 20 out of 80 results

article

Sural nerve sensory response in diabetic distal symmetrical polyneuropathy

Yun‐Ru Lai, Chih‐Cheng Huang, Wen‐Chan Chiu, Rue‐Tsuan Liu, more

Introduction The sural sensory nerve action potential (SNAP) amplitude is a measure of the number of axons. We tested the hypothesis that sural SNAP amplitude can be used as a marker in screening, severity evaluation, and follow‐up of diabetic distal symmetrical polyneuropathy (DSPN). Methods Patients with type 2 diabetes underwent nerve conduction studies and were followed for 6 years. Composite...

article

An actin-binding protein ESPN is an independent prognosticator and regulates cell growth for esophageal squamous cell carcinoma

Shau-Hsuan Li, Hung-I Lu, Wan-Ting Huang, Yen-Hao Chen, more

Cancer Cell International > 2018 > 18 > 1 > 1-9

Background ESPN (Espin), an actin filament-binding protein, plays an important role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Recent few studies show that ESPN regulates metastasis and cell proliferation in melanoma. However,...

article

Reduced lateral occipital gray matter volume is associated with physical frailty and cognitive impairment in Parkinson’s disease

Yueh-Sheng Chen, Hsiu-Ling Chen, Cheng-Hsien Lu, Meng-Hsiang Chen, more

European Radiology > 2019 > 29 > 5 > 2659-2668

Introduction To investigate the structural changes of the brain that correlate with physical frailty and cognitive impairments in Parkinson’s disease (PD) patients. Methods Sixty-one PD patients and 59 age- and sex-matched healthy controls were enrolled. For each participant, a frailty assessment using Fried’s criteria and comprehensive neuropsychological testing using the Wechsler Adult Intelligence...

article

Interaction of systemic oxidative stress and mesial temporal network degeneration in Parkinson’s disease with and without cognitive impairment

Pi-Ling Chiang, Hsiu-Ling Chen, Cheng-Hsien Lu, Yueh-Sheng Chen, more

Journal of Neuroinflammation > 2018 > 15 > 1 > 1-11

Background To identify the vulnerable areas associated with systemic oxidative stress and further disruption of these vulnerable areas by measuring the associated morphology and functional network alterations in Parkinson’s disease (PD) patients with and without cognitive impairment. Methods This prospective study was approved by the institutional review board of KCGMH, and written informed consent...

article

Increased circulating endothelial progenitor cells and improved short-term outcomes in acute non-cardioembolic stroke after hyperbaric oxygen therapy

Chen-Yu Chen, Re-Wen Wu, Nai-Wen Tsai, Mel S. Lee, more

Journal of Translational Medicine > 2018 > 16 > 1 > 1-9

Background Acute ischemic stroke is a leading cause of mortality and long-term disability, and profiles of endothelial progenitor cells (EPCs) reflect the degree of endothelial impairment. This study tested the hypothesis that hyperbaric oxygen therapy (HBOT) both improves the clinical short-term outcomes and increases the number of circulating EPCs and antioxidant capacity. Methods The numbers...

article

Decreased cerebral blood flow and improved cognitive function in patients with end-stage renal disease after peritoneal dialysis: An arterial spin-labelling study

Ben-Chung Cheng, Po-Cheng Chen, Pei-Chin Chen, Cheng-Hsien Lu, more

European Radiology > 2019 > 29 > 3 > 1415-1424

Objectives The aim of this study was to evaluate the relationship between cognitive impairment and brain perfusion using arterial spin labelling (ASL) in end-stage renal disease (ESRD) patients undergoing PD. Methods ESRD patients undergoing PD were recruited. Laboratory screening, neuropsychological tests and ASL magnetic resonance imaging (MRI) were conducted prior to and after 6 months of PD...

article

Tumor Volume Changes During and After Temozolomide Treatment for Newly Diagnosed Higher-Grade Glioma (III and IV)

Hung-Chen Wang, Yu-Tsai Lin, Wei-Che Lin, Ren-Wen Ho, more

World Neurosurgery > 2018 > 114 > C > e766-e774

A standard post-concomitant radiochemotherapy involving adjuvant temozolomide (TMZ) was stopped after 6 cycles for high-grade gliomas (HGG). Several studies demonstrated that prolonged TMZ treatment increased survival for these patients.This retrospective study aimed to compare changes in tumor volume during and after adjuvant TMZ treatment and overall survival (OS).There were 90 patients were administered...

article

Intraoperative identification and definition of “functional” lymphatic collecting vessels for supermicrosurgical lymphatico‐venous anastomosis in treating lymphedema patients

Johnson Chia‐Shen Yang, Shao‐Chun Wu, Min‐Hsien Chiang, Wei‐Che Lin, more

Journal of Surgical Oncology > 117 > 5 > 994 - 1000

Background For current lymphatico‐venous anastomosis (LVA), the identification of “functional” lymphatic collecting vessels (LCVs) is mainly based on indocyanine green (ICG) lymphography. However, some of the non‐ICG enhanced LCVs utilized for LVA were found to have visual lymphatic flow. Objectives Should non‐ICG enhanced, but flow‐positive LCVs be considered functional as well? Methods A retrospective...

article

Reduced gray matter volume and respiratory dysfunction in Parkinson’s disease: a voxel-based morphometry study

Sieh-Yang Lee, Meng-Hsiang Chen, Pi-Ling Chiang, Hsiu-Ling Chen, more

BMC Neurology > 2018 > 18 > 1 > 1-8

Background The respiratory dysfunction of patients with Parkinson’s disease (PD) has drawn increasing attention. This study evaluated the relationship between gray matter volume (GMV), as determined by voxel-based morphometry (VBM), and respiratory dysfunction in patients with PD and correlated it with systemic inflammatory markers. Methods Whole-brain VBM analysis was performed on 3-dimensional...

article

Extraction of large-scale structural covariance networks from grey matter volume for Parkinson’s disease classification

Pei-Lin Lee, Kun-Hsien Chou, Cheng-Hsien Lu, Hsiu-Ling Chen, more

European Radiology > 2018 > 28 > 8 > 3296-3305

Objectives To identify disease-related spatial covariance patterns of grey matter volume as an aid in the classification of Parkinson’s disease (PD). Methods Seventy structural covariance networks (SCNs) based on grey matter volume covariance patterns were defined using independent component analysis with T1-weighted structural MRI scans (discovery sample, 70 PD patients and 70 healthy controls)...

article

Effect of Baroreceptor Sensitivity on Outcomes in Patients with Acute Spontaneous Intracerebral Hemorrhage

Yun-Ru Lai, Yu-Jun Lin, Fu-Yuan Shih, Hung-Chen Wang, more

World Neurosurgery > 2018 > 109 > C > e754-e760

Reduced baroreflex sensitivity (BRS) has been reported in patients with acute cardiovascular events. We tested the hypothesis that BRS is substantially reduced in patients with spontaneous intracerebral hemorrhage (ICH) and that BRS can predict treatment outcomes.We examined BRS and other cardiovascular autonomic parameters in 35 patients with ICH over the course of 30 days. Cardiovascular autonomic...

article

Systemic inflammation and alterations to cerebral blood flow in obstructive sleep apnea

Hsiu‐Ling Chen, Hsin‐Ching Lin, Cheng‐Hsien Lu, Pei‐Chin Chen, more

Journal of Sleep Research > 26 > 6 > 789 - 798

Systemic inflammation and alterations to regional cerebral blood flow (CBF) have been reported previously in obstructive sleep apnea (OSA). This study utilized arterial spin labelling (ASL) perfusion magnetic resonance imaging (MRI) to evaluate CBF in OSA patients and determine its relationship with systemic inflammation. Twenty male patients with moderate and severe OSA [apnea–hypopnea index (AHI)...

article

Risk Factors for Ventriculoperitoneal Shunt Dependency in Patients with Spontaneous Cerebellar Hemorrhage

Shih-Yuan Hsu, Hsin-Huan Chang, Fu-Yuan Shih, Yu-Jun Lin, more

World Neurosurgery > 2017 > 105 > C > 63-68

Hydrocephalus is a common complication after spontaneous cerebellar hemorrhage (CH). This study focused on predicting ventriculoperitorneal (VP) shunt dependency in patients with spontaneous CH.Ninety-nine patients with spontaneous CH were evaluated in this retrospective study. A comparison between patients with and those without VP shunt dependency during hospitalization was made.VP shunt–dependent...

article

White matter damage and systemic inflammation in Parkinson’s disease

Pi-Ling Chiang, Hsiu-Ling Chen, Cheng-Hsien Lu, Pei-Chin Chen, more

BMC Neuroscience > 2017 > 18 > 1 > 1-11

Background Systemic inflammation and white matter (WM) alterations have been noted as effects of Parkinson’s disease (PD). This study sought to evaluate WM integrity in PD patients using diffusion tensor imaging (DTI) and to assess its relationship with systemic inflammation. Methods Sixty-six patients with PD (23 men and 43 women) and 67 healthy volunteers (29 men and 38 women) underwent blood...

chapter

A radio transceiver architecture for coexistence of 4G-LTE and 5G systems used in mobile devices

Chien-Chang Huang, Wei-Che Lin

2017 IEEE MTT-S International Microwave Symposium (IMS) > 2056 - 2058

2017 IEEE/MTT-S International Microwave Symposium - IMS 2017

This paper presents a radio transceiver architecture in mobile devices for coexistence of 4G-LTE and 5G systems, with fewer extra components and easier circuit implementations. The radio front-end is divided into two parts depending on the frequency bands, below 6 GHz or higher than 10 GHz even to millimeter-waves. Direct IQ modulation/demodulation blocks, baseband analog circuitries and frequency...

article

Parkinson’s disease: diagnostic utility of volumetric imaging

Wei-Che Lin, Kun-Hsien Chou, Pei-Lin Lee, Nai-Wen Tsai, more

Neuroradiology > 2017 > 59 > 4 > 367-377

Purpose This paper aims to examine the effectiveness of structural imaging as an aid in the diagnosis of Parkinson’s disease (PD). Methods High-resolution T₁-weighted magnetic resonance imaging was performed in 72 patients with idiopathic PD (mean age, 61.08 years) and 73 healthy subjects (mean age, 58.96 years). The whole brain was parcellated into 95 regions of interest using composite anatomical...

article

Impact of inflammation and oxidative stress on carotid intima‐media thickness in obstructive sleep apnea patients without metabolic syndrome

Ya‐Ting Chang, Hsin‐Ching Lin, Wen‐Neng Chang, Nai‐Wen Tsai, more

Journal of Sleep Research > 26 > 2 > 151 - 158

Obstructive sleep apnea (OSA) increases the risk of cardiovascular diseases, and carotid intima‐media thickness (IMT) is a good indicator of the severity of atherosclerotic disease. This study tested the hypothesis that inflammation and oxidative stress determined carotid IMT in patients with OSA. The carotid IMT, mean systolic and diastolic pressure (night and morning) were significantly higher and...

chapter

A regenerative braking system for switched reluctance machine applied to electric vehicles

Min-Fu Hsieh, Po-Ying Li, Hao-Yu Ting, Chung-Chan Hsu, more

2016 19th International Conference on Electrical Machines and Systems (ICEMS) > 1 - 6

2016 19th International Conference on Electrical Machines and Systems (ICEMS)

This paper presents the control strategies of switched reluctance machine (SRM) applied to EV traction for operations in generating mode. The proposed approach is capable of preventing the exciting current entering the ascending-inductance region so that the unwanted motoring action can be utterly avoided. This can enhance the efficiency of energy recovery during the braking period and is beneficial...

chapter

Investigation of reluctance integrated starter/generator based on higher rotor pole number and dual air gaps design

Po-Wei Huang, Zhi-Yong Zhang, Wei-Che Lin, Mi-Ching Tsai

2016 19th International Conference on Electrical Machines and Systems (ICEMS) > 1 - 4

2016 19th International Conference on Electrical Machines and Systems (ICEMS)

The switched reluctance type integrated starter generator (SRISG) has the potential to be applied in hybrid electric vehicles for its robust structure, and it does not feature a magnet. In this paper, a new double-gap SRISG design that can provide higher power is presented. Characteristics, such as torque ripple, charging ability, and efficiency, are investigated by both 2D and 3D finite element analysis...

article

The Therapeutic Benefit of Radical Resection for T4b Oral Cavity Squamous Cell Carcinoma with Partial or Complete Response After Radical Chemo-Intensity-Modulated Radiotherapy (IMRT)

Fu-Min Fang, Hui-Ching Chuang, Shang-Yu Chou, Tai-Lin Huang, more

Annals of Surgical Oncology > 2016 > 23 > 5 > 866-873

Background This study investigated the therapeutic benefit of radical resection (SRR) for clinical T4b oral cavity squamous cell carcinoma (OSCC) with partial or complete response after radical chemoradiotherapy (CRT). Methods At the authors’ institution, 79 patients with newly diagnosed non-metastatic T4b OSCC were treated with CRT from January 2009 to December 2014. All of them were irradiated...

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INFONA - science communication portal

Search results for: Wei-Che Lin

Sural nerve sensory response in diabetic distal symmetrical polyneuropathy

An actin-binding protein ESPN is an independent prognosticator and regulates cell growth for esophageal squamous cell carcinoma

Reduced lateral occipital gray matter volume is associated with physical frailty and cognitive impairment in Parkinson’s disease

Interaction of systemic oxidative stress and mesial temporal network degeneration in Parkinson’s disease with and without cognitive impairment

Increased circulating endothelial progenitor cells and improved short-term outcomes in acute non-cardioembolic stroke after hyperbaric oxygen therapy

Decreased cerebral blood flow and improved cognitive function in patients with end-stage renal disease after peritoneal dialysis: An arterial spin-labelling study

Tumor Volume Changes During and After Temozolomide Treatment for Newly Diagnosed Higher-Grade Glioma (III and IV)

Intraoperative identification and definition of “functional” lymphatic collecting vessels for supermicrosurgical lymphatico‐venous anastomosis in treating lymphedema patients

Reduced gray matter volume and respiratory dysfunction in Parkinson’s disease: a voxel-based morphometry study

Extraction of large-scale structural covariance networks from grey matter volume for Parkinson’s disease classification

Effect of Baroreceptor Sensitivity on Outcomes in Patients with Acute Spontaneous Intracerebral Hemorrhage

Systemic inflammation and alterations to cerebral blood flow in obstructive sleep apnea

Risk Factors for Ventriculoperitoneal Shunt Dependency in Patients with Spontaneous Cerebellar Hemorrhage

White matter damage and systemic inflammation in Parkinson’s disease

A radio transceiver architecture for coexistence of 4G-LTE and 5G systems used in mobile devices

Parkinson’s disease: diagnostic utility of volumetric imaging

Impact of inflammation and oxidative stress on carotid intima‐media thickness in obstructive sleep apnea patients without metabolic syndrome

A regenerative braking system for switched reluctance machine applied to electric vehicles

Investigation of reluctance integrated starter/generator based on higher rotor pole number and dual air gaps design

The Therapeutic Benefit of Radical Resection for T4b Oral Cavity Squamous Cell Carcinoma with Partial or Complete Response After Radical Chemo-Intensity-Modulated Radiotherapy (IMRT)

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