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Biomedizinische Analyse Der Gasdruck lässt sich als Auslesesignal für ein hoch empfindliches bioanalytisches Instrument verwenden, wie C. Yang et al. in ihrer Zuschrift auf S. 10594 ff. demonstrieren. Die Kombination von H2O2‐Zersetzung mit einem Antikörper‐Assay ermöglicht die Detektion verschiedener Analyten.
Herein, we demonstrate that a very familiar, yet underutilized, physical parameter—gas pressure—can serve as signal readout for highly sensitive bioanalysis. Integration of a catalyzed gas‐generation reaction with a molecular recognition component leads to significant pressure changes, which can be measured with high sensitivity using a low‐cost and portable pressure meter. This new signaling strategy...
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