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The mammary carcinogenicity of two diol epoxide metabolites of the commonly occurring environmental carcinogen benzo[j]fluoranthene (BjF) was investigated by direct application to the tissue beneath the mammary glands of female CD rats. The compounds tested were trans-4,5-dihydroxy-anti-6,6a-epoxy-4,5,6,6a-tetrahydroBjF (BjF-4,5-DE) andtrans -9,10-diihydroxy-anti-11,12-epoxy-9,10,11,12-tetrahydroBjF...
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