Search results for: Kristian Jensen

Items from 1 to 19 out of 19 results

article

Autism comorbidities show elevated female‐to‐male odds ratios and are associated with the age of first autism diagnosis

Eya‐Mist Rødgaard, Kristian Jensen, Kamilla Woznica Miskowiak, Laurent Mottron

Acta Psychiatrica Scandinavica > 144 > 5 > 475 - 486

Objective To investigate the association between the comorbidity rates in autism and sex, birth year and the age at which autism was first diagnosed and compare the relative impact of each. Method Using the Danish National Patient Registry, cumulative incidences up to the age of 16 for 11 comorbid conditions (psychosis, affective disorders, anxiety disorders, conduct disorder, eating disorders,...

article

Point‐spread function convolution to simulate prestack depth migrated images: A validation study

Kristian Jensen, Isabelle Lecomte, Leiv Jacob Gelius, Tina Kaschwich

Geophysical Prospecting > 69 > 8-9 > 1571 - 1590

Seismic migration commonly yields an incomplete reconstruction of the Earth model due to restricted survey aperture, band‐limited frequency content and propagation effects. This affects both illumination and resolution of the structures of interest. Through the application of spatial convolution operators commonly referred to as point‐spread functions, simulated prestack depth‐migrated images incorporating...

article

Seismic on floating ice: data acquisition versus flexural wave noise

Tor Arne Johansen, Bent Ole Ruud, Ronny Tømmerbakke, Kristian Jensen

Geophysical Prospecting > 67 > 3 > 532 - 549

Geophysical surveying of the Arctic will become increasingly important in future prospecting and monitoring of the terrestrial and adjacent areas in this hemisphere. Seismic data acquired on floating ice are hampered with extensive noise due to ice vibrations related to highly dispersive ice flexural waves generated by the seismic source. Several experiments have been conducted on floating ice in...

article

siRNA-mediated inhibition of SREBP cleavage-activating protein reduces dyslipidemia in spontaneously dysmetabolic rhesus monkeys

Beth Ann Murphy, Marija Tadin-Strapps, Kristian Jensen, Robin Mogg, more

Metabolism > 2017 > 71 > C > 202-212

SREBP cleavage-activating protein (SCAP) is a cholesterol binding endoplasmic reticulum (ER) membrane protein that is required to activate SREBP transcription factors. SREBPs regulate genes involved in lipid biosynthesis. They also influence lipid clearance by modulating the expression of LDL receptor (LDLR) and proprotein convertase subtilisin/kexin type 9 (PCSK9) genes. Inhibiting SCAP decreases...

article

Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli

Lisa Gerner, Steffi Munack, Koen Temmerman, Ann-Marie Lawrence-Dörner, more

Data in Brief > 2016 > 8 > C > 733-740

Calcium/calmodulin-dependent kinase kinase 2 (CaMKK2) has been implicated in a range of conditions and pathologies from prostate to hepatic cancer. Here, we describe the expression in Escherichia coli and the purification protocol for the following constructs: full-length CaMKK2 in complex with CaM, CaMKK2 ‘apo’, CaMKK2 (165-501) in complex with CaM, and the CaMKK2 F267G mutant. The protocols described...

article

Using the fluorescent properties of STO-609 as a tool to assist structure-function analyses of recombinant CaMKK2

Lisa Gerner, Steffi Munack, Koen Temmerman, Ann-Marie Lawrence-Dörner, more

Biochemical and Biophysical Research Communications > 2016 > 476 > 2 > 102-107

Calcium/calmodulin-dependent kinase kinase 2 (CaMKK2) has been implicated in the regulation of metabolic activity in cancer and immune cells, and affects whole-body metabolism by regulating ghrelin-signalling in the hypothalamus. This has led to efforts to develop specific CaMKK2 inhibitors, and STO-609 is the standardly used CaMKK2 inhibitor to date. We have developed a novel fluorescence-based assay...

chapter

Mobile Context Toolbox

Jakob Eg Larsen, Kristian Jensen

Lecture Notes in Computer Science > Smart Sensing and Context > Context-Aware Frameworks in Mobile Environments > 193-206

We describe an open framework utilizing sensors and application data on S60 mobile phones enabling rapid prototyping of context-aware mobile applications. The framework has an extensible layered architecture allowing new sensors and features to be added to the context framework as they become available on mobile phone platforms. The framework provides access to multiple sensors to derive user context,...

article

Rationale and design of the ADEX study: Preserving quality of life, physical health and functional ability in Alzheimer's disease—The effect of physical exercise

Kristine Hoffmann, Kristian Jensen, Nanna Aue Sobol, Asmus Vogel, more

Alzheimer's & Dementia > 2012 > 8 > 4(S) > P576

article

Finding Acoustically Stable Areas Through Empirical Orthogonal Function (EOF) Classification

Jan Kristian Jensen, Karl Thomas Hjelmervik, Petter Ostenstad

IEEE Journal of Oceanic Engineering > 2012 > 37 > 1 > 103 - 111

Validity of sonar performance models is generally limited by environmental uncertainty, and particularly uncertainty in the sound-speed profile (SSP). Rapid environmental assessment (REA) missions, e.g., using gliders, and advanced ocean models may be used to reduce this uncertainty before sonar operation in hostile waters. This work shows how data from ocean models may be used for planning of REA...

article

Classification of acoustically stable areas using empirical orthogonal functions

Karl Thomas Hjelmervik, Jan Kristian Jensen, Petter Østenstad, Atle Ommundsen

Ocean Dynamics > 2012 > 62 > 2 > 253-264

Sonar performance modeling is crucial for submarine and anti–submarine operations. The validity of sonar performance models is generally limited by environmental uncertainty, and particularly uncertainty in the vertical sound speed profile (SSP). Rapid environmental assessment (REA) products, such as oceanographic surveys and ocean models may be used to reduce this uncertainty prior to sonar operations...

article

Identifying Static and Kinetic Lipid Phenotypes by High Resolution UPLC–MS: Unraveling Diet-Induced Changes in Lipid Homeostasis by Coupling Metabolomics and Fluxomics

Jose M. Castro-Perez, Thomas P. Roddy, Vinit Shah, David G. McLaren, more

Journal of Proteome Research > 2011 > 10 > 9 > 4281 - 4290

article

A Phase III Extension Trial With a 1-Arm Crossover From Leuprolide to Degarelix: Comparison of Gonadotropin-Releasing Hormone Agonist and Antagonist Effect on Prostate Cancer

E. David Crawford, Bertrand Tombal, Kurt Miller, Laurent Boccon-Gibod, more

The Journal of Urology > 2011 > 186 > 3 > 889-897

We investigated the efficacy and safety of degarelix treatment and the effects of switching from leuprolide to degarelix in an ongoing extension study with a median 27.5-month followup of a pivotal 1-year prostate cancer trial. Patients who completed a 1-year pivotal phase III trial continued on the same monthly degarelix maintenance dose (160 or 80 mg in 125 each), or were re-randomized from leuprolide...

chapter

Estimating human predictability from mobile sensor data

Bjorn Sand Jensen, Jakob Eg Larsen, Kristian Jensen, Jan Larsen, more

2010 IEEE International Workshop on Machine Learning for Signal Processing > 196 - 201

2010 IEEE International Workshop on Machine Learning for Signal Processing (MLSP)

Quantification of human behavior is of prime interest in many applications ranging from behavioral science to practical applications like GSM resource planning and context-aware services. As proxies for humans, we apply multiple mobile phone sensors all conveying information about human behavior. Using a recent, information theoretic approach it is demonstrated that the trajectories of individual...

article

Additional Analysis of the Secondary End Point of Biochemical Recurrence Rate in a Phase 3 Trial (CS21) Comparing Degarelix 80mg Versus Leuprolide in Prostate Cancer Patients Segmented by Baseline Characteristics

Bertrand Tombal, Kurt Miller, Laurent Boccon-Gibod, Fritz Schröder, more

European Urology > 2010 > 57 > 5 > 836-842

Recent data suggest prostate-specific antigen (PSA) progression may predict overall survival in prostate cancer patients.To compare the activity of degarelix and leuprolide regarding PSA recurrence-free survival.Phase 3, 1-yr, multicentre, randomised, open-label trial comparing the efficacy and safety of degarelix at 240mg for 1 mo, and then 80mg monthly (240/80mg); degarelix at 240mg for 1 mo, and...

article

A 1-Year, Open Label, Randomized Phase II Dose Finding Study of Degarelix for the Treatment of Prostate Cancer in North America

Marc Gittelman, Peter J. Pommerville, Bo-Eric Persson, Jens-Kristian Jensen, more

The Journal of Urology > 2008 > 180 > 5 > 1986-1992

Degarelix is a gonadotropin-releasing hormone receptor antagonist (blocker) with rapid onset of action suppressing gonadotropins, testosterone and prostate specific antigen in prostate cancer. In the present open label, randomized study in North America we evaluated the efficacy and safety of a starting dose of 200 mg degarelix followed by monthly injections of 60 or 80 mg during 1 year of prostate...

article

Degarelix: A Novel Gonadotropin-Releasing Hormone (GnRH) Receptor Blocker—Results from a 1-yr, Multicentre, Randomised, Phase 2 Dosage-Finding Study in the Treatment of Prostate Cancer

Hendrik Van Poppel, Bertrand Tombal, Jean J. de la Rosette, Bo-Eric Persson, more

European Urology > 2008 > 54 > 4 > 805-815

Degarelix is a gonadotropin-releasing hormone antagonist (GnRH receptor blocker) with immediate onset of action, suppressing gonadotropins, testosterone, and prostate-specific antigen (PSA) in prostate cancer.To determine the efficacy and safety of initial doses of 200mg or 240mg of degarelix and thereafter monthly subcutaneous maintenance doses of 80mg, 120mg, or 160mg of degarelix for the treatment...

article

Norwegian METOC distribution system: Sophisticated integration through simple mechanisms

Jan Kristian Jensen, Kjell Røang, Reinoud Bokhorst, Richard Olsen, more

Journal of Marine Systems > 2008 > 69 > 1-2 > 146-153

An exceedingly versatile and flexible system for meteorological and oceanographic data distribution and processing has been built for the Norwegian Navy, with special emphasis on how operational forecasting products may be distributed effectively to marine users. This distribution system meets an extremely wide range of user requirements, from visualization in web browser to sophisticated integration...

article

The Gutenberg Bibles: Analysis of the Illuminations and Inks Using Raman Spectroscopy

Tracey D. Chaplin, Robin J. H. Clark, David Jacobs, Kristian Jensen, more

Analytical Chemistry > 2005 > 77 > 11 > 3611 - 3622

article

Applying phage display technology in aging research

Peter Kristensen, Peter Ravn, Kim Bak Jensen, Kristian Jensen

Biogerontology > 2000 > 1 > 1 > 67-78

Filamentous bacteriophage offers the possibility oflinking genotype with phenotype in one geneticpackage. By creating a library of different proteinsas fusion to one of the coat proteins of filamentousbacteriophage it becomes possible to isolate proteinsbased on their binding characteristics. Phagedisplayed libraries of varying formats, ranging fromsmall peptides to antibody fragments, have beenselected...

Filter options

Publication date

Set your own date range

INFONA - science communication portal

Search results for: Kristian Jensen

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Publication type

Keywords

Data set

Journal

Reporting an error / abuse

Sending the report failed

Accessibility options