Search results for: Werner G. Kuhr

Items from 1 to 12 out of 12 results

article

Independently-addressable micron-sized biosensor elements

C. Brandon Davis, Lisa M. Shamansky, Steven Rosenwald, Joan K. Stuart, more

Biosensors and Bioelectronics > 2003 > 18 > 10 > 1299 - 1307

With the continuing development of micro-total analysis systems and sensitive biosensing technologies, it is often desirable to immobilize biomolecules onto a surface in a small well-defined area. A novel method was developed to electrochemically attach DNA probes to micron-sized regions of a gold surface using biotin-LC-hydrazide (BH). Previously, we have found that the radical produced during the...

article

Performance of Pyrolyzed Photoresist Carbon Films in a Microchip Capillary Electrophoresis Device with Sinusoidal Voltammetric Detection

Nicole E. Hebert, Brian Snyder, Richard L. McCreery, Werner G. Kuhr, more

Analytical Chemistry > 2003 > 75 > 16 > 4265 - 4271

article

A Microchip Electrophoresis Device with Integrated Electrochemical Detection: A Direct Comparison of Constant Potential Amperometry and Sinusoidal Voltammetry

Nicole E. Hebert, Werner G. Kuhr, Sara A. Brazill

Analytical Chemistry > 2003 > 75 > 14 > 3301 - 3307

article

Measurements of Electron-Transfer Rates of Charge-Storage Molecular Monolayers on Si(100). Toward Hybrid Molecular/Semiconductor Information Storage Devices

Kristian M. Roth, Amir A. Yasseri, Zhiming Liu, Rajeev B. Dabke, more

Journal of the American Chemical Society > 2003 > 125 > 2 > 505 - 517

article

Sinusoidal voltammetry: - a frequency based electrochemical detection technique

Sara A. Brazill, Sharin E. Bender, Nicole E. Hebert, John K. Cullison, more

Journal of Electroanalytical Chemistry > 2002 > 531 > 2 > 119 - 132

Sinusoidal voltammetry is an electrochemical technique, which uses a large amplitude sinusoid as the potential waveform and performs data analysis in the frequency domain. When the amplitude of the applied potential waveform is large (i.e. >50 mV) the current-potential behavior of the electrochemical interface is extremely non-linear. As a result the faradaic response exhibits signal intensity...

article

Comparison of Electron-Transfer and Charge-Retention Characteristics of Porphyrin-Containing Self-Assembled Monolayers Designed for Molecular Information Storage

Kristian M. Roth, Daniel T. Gryko, Christian Clausen, Junzhong Li, more

The Journal of Physical Chemistry B > 2002 > 106 > 34 > 8639 - 8648

article

A Single Base Extension Technique for the Analysis of Known Mutations Utilizing Capillary Gel Electrophoreisis with Electrochemical Detection

Sara A. Brazill, Werner G. Kuhr

Analytical Chemistry > 2002 > 74 > 14 > 3421 - 3428

article

Characterization of Charge Storage in Redox-Active Self-Assembled Monolayers

Kristian M. Roth, Jonathan S. Lindsey, David F. Bocian, Werner G. Kuhr

Langmuir > 2002 > 18 > 10 > 4030 - 4040

article

Immobilization and detection of DNA on microfluidic chips

Lisa M. Shamansky, C. Brandon Davis, Joan K. Stuart, Werner G. Kuhr

Talanta > 2001 > 55 > 5 > 909 - 918

With the rapid development of micro-Total Analysis Systems (μTAS) and sensitive DNA recognition technologies, it is possible to immobilize DNA probes to small areas of surfaces other than silicon. To this end, photolithographic techniques were used to derivatize micron-sized, spatially segregated DNA recognition elements in Polydimethylsiloxane (PDMS) microfluidic structures. UV light was used to...

article

Capillary Gel Electrophoresis with Sinusoidal Voltammetric Detection: A Strategy To Allow Four-“Color” DNA Sequencing

Sara A. Brazill, Paul H. Kim, Werner G. Kuhr

Analytical Chemistry > 2001 > 73 > 20 > 4882 - 4890

article

Development of sub-micron patterned carbon electrodes for immunoassays

Narasaiah Dontha, Wilbur B. Nowall, Werner G. Kuhr

Journal of Pharmaceutical and Biomedical Analysis > 1999 > 19 > 1-2 > 83-91

Sub-micron sized domains of a carbon surface are derivatized with antibodies using biotin/avidin technology. These sites are spatially-segregated from, and directly adjacent to, electron transfer sites on the same electrode surface. The distance between these electron transfer sites and enzyme-loaded domains are kept to a minimum (e.g. less than a micron) to maintain the high sensitivity required...

article

Background-subtraction of fast-scan cyclic staircase voltammetry at protein-modified carbon-fiber electrodes

Mark A. Hayes, Eric W. Kristensen, Werner G. Kuhr

Biosensors and Bioelectronics > 1998 > 13 > 12 > 1297-1305

Background-subtraction techniques were applied to the voltammetry of nicotinamide adenine dinucleotide (NADH) at protein-modified carbon-fiber microelectrodes. The background currents at carbon-fiber electrodes were stable and voltammetric scans immediately before or after the analyte were effectively used for background subtraction. Digital step-potential waveforms were used to excite these carbon-fiber...

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Search results for: Werner G. Kuhr

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