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Lab-on-chip technology has tremendous potential for point-of-care and in-field medical diagnostics, but the uptake of such technologies is hampered by the high cost and large size of the instrumentation conventionally required. In the present work we demonstrate an instrument that fully automates sample preparation, enzymatic digestion and electrophoresis to implement DNA sizing and restriction fragment...
Electrophoresis is a powerful method that has seen a wide range of applications, often in automated genetic diagnostic instruments that require the use of a replaceable sieving matrix. The power and simplicity of electrophoresis as an analysis technique would be ideal for highly integrated and low‐cost analysis systems if the method could be implemented in microfluidics on the scale of several mm...
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