Search results for: Muhammad Ashraf

Items from 1 to 20 out of 474 results

article

An advanced automation platform coupled with mass spectrometry for investigating in vitro human skin permeation of UV filters and excipients in sunscreen products

Jinhui Zhang, Yang Yang, Muhammad Ashraf, Celia N. Cruz, more

Rapid Communications in Mass Spectrometry > 36 > 11 > n/a - n/a

Rationale Systemic absorption of UV‐filtering chemicals following topical application of sunscreens may present a safety concern. The Food and Drug Administration (FDA) had recommended an in vitro skin permeation test (IVPT) to evaluate the potential of this safety risk for the evaluation of sunscreens prior to clinical studies. Therefore, a sensitive and robust bioanalytical method(s) were required...

article

Mesophilic batch co‐digestion of municipal solid waste and food waste: improved digester performance and stability at optimum organic loading rates

Muhammad Shahbaz, Muhammad Ammar, Shahid Hussain, Toheed Ahmed, more

Journal of Chemical Technology & Biotechnology > 97 > 3 > 633 - 642

BACKGROUND The accumulative municipal solid waste (MSW) production calls for emerging efficient technology for its handling. Anaerobic digestion (AD) of MSW provides effective waste volatilization. The high C/N ratio of MSW and increasing organic loading rates (OLRs) are central AD restrictions that affect the AD process performance, inhibition due to aggregation of volatile fatty acids (VFAs), and...

article

Single in‐line biomass probe detects CHO cell growth by capacitance and bacterial contamination by conductivity in bioreactor

Caitlin Morris, Chikkathur N. Madhavarao, Seongkyu Yoon, Muhammad Ashraf

Biotechnology Journal > 16 > 12 > n/a - n/a

Background Real time process data facilitates timely decisions, enables better process control, and can increase quality assurance. Biological drugs (mol. Wt. ≥ 40 kDa) are manufactured using mammalian cells such as Chinese hamster ovary (CHO) cells in bioreactors and have significant risks of contamination during processing. In such processes, in‐line monitoring of biomass can provide real‐time...

article

Synthesis of benzimidazole based hydrazones as non‐sugar based α‐glucosidase inhibitors: Structure activity relation and molecular docking

Muhammad Umair Ahmad, Muhammad Rafiq, Bakhtawar Zahra, Muhamamd Islam, more

Drug Development Research > 82 > 7 > 1033 - 1043

In search for α‐glucosidase inhibitors used in the treatment of diabetes mellitus, a series of unique benzimidazole based hydrazones derivatives were synthesized (5a‐5p), which were then investigated for their in vitro α‐glucosidase inhibitory potential. The compounds of interest were characterized by modern spectroscopic approaches including CHN, ¹HNM R, ¹³CN MR and FTIR. The structure of compound...

article

HSP70‐16 and VDAC3 jointly inhibit seed germination under cold stress in Arabidopsis

Muhammad Ashraf, Qionglei Mao, Jun Hong, Lei Shi, more

Plant, Cell & Environment > 44 > 11 > 3616 - 3627

Abscisic acid (ABA) transport plays a crucial role in seed germination under unfavourable conditions such as cold stress. Both heat shock protein 70 (HSP70) and voltage‐dependent anion channel (VDAC) protein are involved in cold stress responses in Arabidopsis. However, their roles in seed germination with regard to ABA signaling remain unknown. Here we demonstrated that Arabidopsis HSP70‐16 and VDAC3...

article

Simulation analysis of MHD hybrid CuAl₂O₃/H₂O nanofluid flow with heat generation through a porous media

Kashif Ali, Sohail Ahmad, Kottakkaran Sooppy Nisar, Aftab Ahmed Faridi, more

International Journal of Energy Research > 45 > 13 > 19165 - 19179

Hybrid nanoliquids comprise of better physical strength, mechanical resistance, thermal conductivity, and chemical stability as equated to individual nanoliquids. The present work investigates the MHD laminar flow, containing hybrid nanoparticles, with heat transfer phenomenon over a stretching sheet immersed in a porous medium. The effect of induced magnetic field has also been taken into account...

article

Impact of exogenously applied trehalose on leaf biochemistry, achene yield and oil composition of sunflower under drought stress

Firdos Kosar, Nudrat Aisha Akram, Muhammad Ashraf, Abrar Ahmad, more

Physiologia Plantarum > 172 > 2 > 317 - 333

This study was carried out to assess the influence of trehalose, a non‐reducing disaccharide involved in improving plant stress tolerance, on two cultivars (Hysun 33 and FH 598) of sunflower (Helianthus annuus L.) grown under control and drought stress conditions. At pre‐flowering stage, varying concentrations (10, 20 and 30 mM) of trehalose were applied to the foliage. Drought stress significantly...

article

Peroxidase activity and operation of photo‐protective component of NPQ play key roles in drought tolerance of mung bean [Vigna radiata (L.) Wilcziek]

Hussan Bano, Habib‐ur‐Rehman Athar, Zafar Ullah Zafar, Chukwuma C. Ogbaga, more

Physiologia Plantarum > 172 > 2 > 603 - 614

Developing drought‐tolerant cultivars is mainly restricted due to poor knowledge of the mechanism behind drought tolerance. In the present work, available germplasm of Vigna radiata (mung bean) was screened for drought tolerance using multiple agronomic and physiological parameters and used to selected one drought‐tolerant (NM‐13‐1) and one drought‐sensitive (NM‐54) cultivar for further studies. Plant...

article

Linking changes in chlorophyll a fluorescence with drought stress susceptibility in mung bean [Vigna radiata (L.) Wilczek]

Hussan Bano, Habib‐ur‐Rehman Athar, Zafar Ullah Zafar, Hazem M. Kalaji, more

Physiologia Plantarum > 172 > 2 > 1244 - 1254

In the present study, the mung bean cv. NM‐13‐1^Tol was selected as drought‐tolerant and NM‐54^Sens as drought‐sensitive. The effects of progressive drought (16 days) on the photosystem II (PSII) activity was assessed using OJIP and JIP‐test in the selected two mung bean cultivars differing in drought tolerance. Drought stress reduced the relative water content to 70% (at threshold) and 62% (below the...

article

Thiamin stimulates growth and secondary metabolites in turnip (Brassica rapa L.) leaf and root under drought stress

Munifa Jabeen, Nudrat Aisha Akram, Muhammad Ashraf, Mohammed Nasser Alyemeni, more

Physiologia Plantarum > 172 > 2 > 1399 - 1411

Thiamin, an important member of the vitamin B family, is believed to play a significant role in mitigating environmental stresses including drought stress. In turnip, drought stress causes a reduced growth, biomass yield, pigment content, total phenolics and ascorbic acid (AsA), particularly at 50% field capacity (F.C.) in the two cultivars (cv) studied. However, a significant enhancement was observed...

article

A Generalized Method for High‐Speed Fluorination of Metal Oxides by Spark Plasma Sintering Yields Ta₃O₇F and TaO₂F with High Photocatalytic Activity for Oxygen Evolution from Water

Martin Alexander Lange, Ibrahim Khan, Phil Opitz, Jens Hartmann, more

Advanced Materials > 33 > 20 > n/a - n/a

A general method to carry out the fluorination of metal oxides with poly(tetrafluoroethylene) (PTFE, Teflon) waste by spark plasma sintering (SPS) on a minute scale with Teflon is reported. The potential of this new approach is highlighted by the following results. i) The tantalum oxyfluorides Ta₃O₇F and TaO₂F are obtained from plastic scrap without using toxic or caustic chemicals for fluorination...

article

A High‐Performance Asymmetric Supercapacitor Based on Tungsten Oxide Nanoplates and Highly Reduced Graphene Oxide Electrodes

Muhammad Ashraf, Syed Shaheen Shah, Ibrahim Khan, Md. Abdul Aziz, more

Chemistry – A European Journal > 27 > 23 > 6973 - 6984

Tungsten oxide/graphene hybrid materials are attractive semiconductors for energy‐related applications. Herein, we report an asymmetric supercapacitor (ASC, HRG//m‐WO₃ ASC), fabricated from monoclinic tungsten oxide (m‐WO₃) nanoplates as a negative electrode and highly reduced graphene oxide (HRG) as a positive electrode material. The supercapacitor performance of the prepared electrodes was evaluated...

article

Salinity resistance as a function of ${NH}_{4}^{+} : {NO}_{3}^{-}$ ratio and its impact on yield and quality of tomato (Solanum lycopersicum L.)

Muhammad Ashraf, Urooj Naz, Muhammad Abid, Sher Muhammad Shahzad, more

Journal of Plant Nutrition and Soil Science > 184 > 2 > 246 - 254

Background: Adequate regulation of plant nutrients may constitute a promising approach to overcome the deleterious effects of salinity on plant growth and development. Among these nutrients, nitrogen (N) can be a stand out option to improve plant adaptation to saline environment. However, plant response to N under salinity stress may vary depending upon

{NH}_{4}^{+} : {NO}_{3}^{-}

ratio in the growth medium...

article

Structural and functional responses in sun spurge (Euphorbia helioscopia L.) against post‐emergence herbicides in wheat (Triticum aestivum L.)

Mishal Iftikhar, Iftikhar Ahmad, Mansoor Hameed, Sana Fatima, more

Weed Research > 61 > 2 > 126 - 136

We investigated changes in plant morphology, anatomy and physiology in a commonly occurring weed, Euphorbia helioscopia L. due to exposure to post‐emergence herbicides. Weed plants were sprayed with one of the following herbicides: pyrimidinyl sulphonylharnstoffe (PS), tribenuron‐methyl (TM), fluroxypyr‐methyl tribenuron‐methyl (FMTM) and bromoxynil (Br). The PS treatment significantly decreased plant...

article

Patient safety culture amongst dental students and interns in Dammam, Saudi Arabia

Reem AlOlayan, Albandri Alahmad, Danah Buali, Faisal Alonaizan, more

European Journal of Dental Education > 25 > 1 > 175 - 182

Objective To evaluate awareness and attitudes of dental students and interns about patient safety culture in Dammam, Saudi Arabia. Materials and methods This cross‐sectional study was conducted on 272 undergraduate dental students and interns using the Safety Attitudes Questionnaire (SAQ) from November 2019 to January 2020. The SAQ consists of six domains: teamwork climate, safety climate, job...

article

Traumatic dental injuries in the Eastern Region of Saudi Arabia: Factors influencing teachers’ management practices

Balgis Gaffar, Jehan AlHumaid, Muhammad Ashraf Nazir, Faisal Alonaizan

Dental Traumatology > 37 > 1 > 65 - 72

Background/Aims Traumatic dental injuries (TDIs) in children frequently occur in schools where teachers can play an important role in their management. Therefore, the aim of this study was to assess schoolteachers’ knowledge and the factors that determine their management of TDIs. Materials and methods This cross‐sectional study was conducted in the Eastern Province of Saudi Arabia from January...

article

Comparative conventional and microwave assisted synthesis of heterocyclic oxadiazole analogues having enzymatic inhibition potential

Jamila Javid, Aziz‐ur‐Rehman, Muhammad A. Abbasi, Sabahat Z. Siddiqui, more

Journal of Heterocyclic Chemistry > 58 > 1 > 93 - 110

A comparative microwave assisted and conventional synthetic strategies were applied to synthesize heterocyclic 1,3,4‐oxadiazole analogues as active anti‐enzymatic agents. Green synthesis of compound 1 was achieved by stirring 4‐methoxybenzenesulfonyl chloride (a) and ethyl piperidine‐4‐carboxylate (b). Compound 1 was converted into respective hydrazide (2) by hydrazine and then into 1,3,4‐oxadiazole...

article

Organocatalyzed Solvent Free and Efficient Synthesis of 2,4,5‐Trisubstituted Imidazoles as Potential Acetylcholinesterase Inhibitors for Alzheimer's Disease

Sania Pervaiz, Sadaf Mutahir, Islam Ullah, Muhammad Ashraf, more

Chemistry & Biodiversity > 17 > 3 > n/a - n/a

The catalytic potential of pyridine‐2‐carboxlic acid has been evaluated for efficient, green and solvent free synthesis of 2,4,5‐trisubstituted imidazole derivatives 3a–3m. The compounds 3a–3m were synthesized by one pot condensation reaction of substituted aromatic aldehydes, benzil, and ammonium acetate in good to excellent yields (74–96 %). To explore the potential of these compounds against Alzheimer's...

article

Biodegradation by Co‐inoculated Bacteria and Fungi Alleviates Adverse Effects of Red‐S3B on Growth and Nitrogen Uptake of Wheat

Maryam Shakeel, Muhammad Imran, Muhammad Ashraf, Najeeb Ullah

CLEAN – Soil, Air, Water > 48 > 3 > n/a - n/a

Textile wastewater contains huge quantities of nitrogen (N)‐containing azo‐dyes. Irrigation of crops with such wastewater adds toxic dyes into our healthy soils. One of the ways to prevent their entry to soils could be these waters after the dyes' biodegradation. Therefore, the present study was conducted to evaluate the impact of textile dyes on wheat growth, dye degradation efficiency of bacteria‐fungi...

article

Integrative roles of nitric oxide and hydrogen sulfide in melatonin‐induced tolerance of pepper (Capsicum annuum L.) plants to iron deficiency and salt stress alone or in combination

Cengiz Kaya, David Higgs, Muhammad Ashraf, Mohammed N. Alyemeni, more

Physiologia Plantarum > 168 > 2 > 256 - 277

There seems to be no report in the literature on the effect of melatonin (MT) in relieving the detrimental effects of combined application of salt stress (SS) and iron deficiency (ID). Therefore, the effect of MT on the accumulation/synthesis of endogenous nitric oxide (NO) and hydrogen sulphide (H₂S) and how far these molecules are involved in MT‐improved tolerance to the combined application of...

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INFONA - science communication portal

Search results for: Muhammad Ashraf

An advanced automation platform coupled with mass spectrometry for investigating in vitro human skin permeation of UV filters and excipients in sunscreen products

Mesophilic batch co‐digestion of municipal solid waste and food waste: improved digester performance and stability at optimum organic loading rates

Single in‐line biomass probe detects CHO cell growth by capacitance and bacterial contamination by conductivity in bioreactor

Synthesis of benzimidazole based hydrazones as non‐sugar based α‐glucosidase inhibitors: Structure activity relation and molecular docking

HSP70‐16 and VDAC3 jointly inhibit seed germination under cold stress in Arabidopsis

Simulation analysis of MHD hybrid CuAl₂O₃/H₂O nanofluid flow with heat generation through a porous media

Impact of exogenously applied trehalose on leaf biochemistry, achene yield and oil composition of sunflower under drought stress

Peroxidase activity and operation of photo‐protective component of NPQ play key roles in drought tolerance of mung bean [Vigna radiata (L.) Wilcziek]

Linking changes in chlorophyll a fluorescence with drought stress susceptibility in mung bean [Vigna radiata (L.) Wilczek]

Thiamin stimulates growth and secondary metabolites in turnip (Brassica rapa L.) leaf and root under drought stress

A Generalized Method for High‐Speed Fluorination of Metal Oxides by Spark Plasma Sintering Yields Ta₃O₇F and TaO₂F with High Photocatalytic Activity for Oxygen Evolution from Water

A High‐Performance Asymmetric Supercapacitor Based on Tungsten Oxide Nanoplates and Highly Reduced Graphene Oxide Electrodes

Salinity resistance as a function of ${NH}_{4}^{+} : {NO}_{3}^{-}$ ratio and its impact on yield and quality of tomato (Solanum lycopersicum L.)

Structural and functional responses in sun spurge (Euphorbia helioscopia L.) against post‐emergence herbicides in wheat (Triticum aestivum L.)

Patient safety culture amongst dental students and interns in Dammam, Saudi Arabia

Traumatic dental injuries in the Eastern Region of Saudi Arabia: Factors influencing teachers’ management practices

Comparative conventional and microwave assisted synthesis of heterocyclic oxadiazole analogues having enzymatic inhibition potential

Organocatalyzed Solvent Free and Efficient Synthesis of 2,4,5‐Trisubstituted Imidazoles as Potential Acetylcholinesterase Inhibitors for Alzheimer's Disease

Biodegradation by Co‐inoculated Bacteria and Fungi Alleviates Adverse Effects of Red‐S3B on Growth and Nitrogen Uptake of Wheat

Integrative roles of nitric oxide and hydrogen sulfide in melatonin‐induced tolerance of pepper (Capsicum annuum L.) plants to iron deficiency and salt stress alone or in combination

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