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Interactions of hydrogen sulfide (HS−/H2S), a reducing signaling species, with superoxide dimutases (SOD) are poorly understood. We applied low-T EPR spectroscopy to examine the effects of HS−/H2S and superoxide radical anion (O2·−) on metallocenters of FeSOD, MnSOD, and CuZnSOD. HS−/H2S did not affect FeSOD, whereas active centers of MnSOD and CuZnSOD were open to this agent. Cu2+ was reduced to...
Early-onset and exclusive breast-feeding provides a significant health benefit to infants compared with infant formulas. The aim of this study was to compare mature breast milk with standard infant formulas by examining their effects on non-vascular smooth muscle contraction and their antioxidative properties.The pharmacologic effects of breast milk and formulas were examined using a model system...
The activities of antioxidant defence enzymes were determined in erythrocytes isolated from types I and II schizophrenic male patients and from healthy controls. Significant differences in superoxide dismutase (SOD) activity (type I: 3284±577; type II: 2959±697 compared with controls: 3778±577; analysis of variance (ANOVA) P<0.001), catalase (CAT) activity (type I: 17.8±1.8 compared to type II:...
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