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Clinically serosa-positive (T3–4) gastric cancer has a poor prognosis. This phase II trial explored the feasibility and safety of preoperative chemotherapy followed by D2 or D3 gastrectomy in this type of gastric cancer.Patients with T3–4 gastric cancer received one course of S-1 (80mg/m 2 daily for 3 weeks) and cisplatin (60mg/m 2 on day 8) chemotherapy and then underwent D2 or D3...
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