Adrenal suppression is a side effect of long‐term use of inhaled corticosteroids (ICS). Hair cortisol concentration (HCC) measurement is a noninvasive tool for measuring adrenal function that may be useful for asthmatic patients who are on long‐term ICS treatment. The aim of this study was to compare HCC between children with and without asthma and to explore the association between HCC...
Adherence to treatment remains important for successful asthma management. Knowledge about asthma medication use and adherence in real‐life offers opportunities to improve asthma treatment in children.
ObjectiveTo describe prescription patterns, adherence and factors of adherence to drugs in children with asthma.
MethodsPopulation‐based cohort study in a Dutch primary care database (IPCI), containing...
Current knowledge on the prevalence of asthma is mainly based on cross‐sectional questionnaire data. Current population‐based data on the incidence of asthma in children are scarce.
To study the incidence, prevalence, and age at diagnosis of asthma in children in the Netherlands over the study period 2000–2012.
A population‐based cohort study was conducted in the...
To develop a computerized prescreening procedure for the identification of possible/probably Hospital Admissions potential Related to Medications (HARMs).
Pairs of drugs and reasons for hospitalization (generated automatically from the PHARMO record linkage database by using two data mining techniques) were assessed manually to determine whether they represented pharmacologically...
PurposeMost electronic health record databases contain unstructured free‐text narratives, which cannot be easily analyzed. Case‐detection algorithms are usually created manually and often rely only on using coded information such as International Classification of Diseases version 9 codes. We applied a machine‐learning approach to generate and evaluate an automated case‐detection algorithm that uses...
Financed by the National Centre for Research and Development under grant No. SP/I/1/77065/10 by the strategic scientific research and experimental development program:
SYNAT - “Interdisciplinary System for Interactive Scientific and Scientific-Technical Information”.