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Diacetyl is a volatile flavour compound that has a characteristic buttery aroma and is widely used in the flavour industry. The aroma of a food plays an important role in food palatability and thus intake. This study investigates the effect of diacetyl on the satiety hormone, glucagon-like peptide (GLP-1), using the enteroendocrine cell line, STC-1. Diacetyl decreased proglucagon mRNA and total GLP-1...
Cholecystokinin (CCK) is a peptide hormone secreted from the I‐cells of the intestine and it has important physiological actions related to appetite regulation and satiety. In this study we used STC‐1 cells to investigate the effects of common dietary‐derived fatty acids (FAs) on I‐cell secretory function and metabolism. We extend earlier studies by measuring the acute and chronic effects of 11 FAs...
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