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CRISPR‐Cas systems are small RNA‐based immune systems that protect prokaryotes from invaders such as viruses and plasmids. We have investigated the features and biogenesis of the CRISPR (cr)RNAs in Streptococcus thermophilus (Sth) strain DGCC7710, which possesses four different CRISPR‐Cas systems including representatives from the three major types of CRISPR‐Cas systems. Our results indicate that...