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The oncoprotein induced transcript 3 (OIT3), also named liver-specific zona pellucida domain-containing protein (LZP), has been shown to be expressed in kidney, and was confirmed to interact with the Tamm–Horsfall glycoprotein (THP). However, the function of OIT3 in kidney remains unclear. In this study we found that serum uric acid level of Oit3 null mice was significantly lower than that in wild...
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