This study investigated the in vivo prophylactic effect of probiotic chocolate on constipation. Rats were administered chocolate containing 2.5 × 1010 CFU g−1 of probiotics daily for 4 weeks and treated with loperamide (5 mg kg−1) daily at the fourth week of treatment.
Probiotic chocolate treatment significantly (P < 0.05) increased the intestinal motility, colon length, fecal...
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