Search results for: Mei Zhou

Items from 1 to 20 out of 540 results

article

Resveratrol attenuates methamphetamine‐induced memory impairment via inhibition of oxidative stress and apoptosis in mice

Qing Zeng, Qi Xiong, Mei Zhou, Xiang Tian, more

Journal of Food Biochemistry > 45 > 2 > n/a - n/a

Methamphetamine (METH) abuse produces serious neurotoxicity to the central nervous system along with long‐term cognitive dysfunction. Resveratrol, a natural polyphenol, has broad application prospects in the treatment of neurodegenerative diseases. Therefore, this study was conducted to investigate whether resveratrol might alleviate METH‐induced memory deficits in vivo. We found that multiple exposures...

article

Characterisation of a novel peptide, Brevinin‐1H, from the skin secretion of Amolops hainanensis and rational design of several analogues

Xinjie Pei, Zijian Gong, Qing Wu, Xiaoling Chen, more

Chemical Biology & Drug Design > 97 > 2 > 273 - 282

As drug‐resistant bacteria have become a serious health problem and have caused thousands of deaths, finding new antibiotics has become an urgent research priority. A novel antimicrobial peptide, named Brevinin‐1H, was identified in the skin secretion of Amolops hainanensis through ‘shotgun’ cloning. It has broad‐spectrum antimicrobial activity against tested micro‐organisms and has anticancer cell...

article

Factors associated with core competencies of emergency‐room nurses in tertiary hospitals in China

Xinxia Li, Mei Zhou, Hui Wang, Wennv Hao

Japan Journal of Nursing Science > 17 > 3 > n/a - n/a

Aim Quantitative studies using validated questionnaires on core competencies of emergency nurses in China are rare and the baseline core competencies must first be evaluated before improvizations to the competencies can be implemented. This study aimed to investigate the factors potentially involved in the level of core competencies of emergency nurses from tertiary hospitals in northwest China....

article

Aspirin promotes tenogenic differentiation of tendon stem cells and facilitates tendinopathy healing through regulating the GDF7/Smad1/5 signaling pathway

Yunjiao Wang, Gang He, Hong Tang, Youxing Shi, more

Journal of Cellular Physiology > 235 > 5 > 4778 - 4789

Tendinopathy is a common musculoskeletal system disorder in sports medicine, but regeneration ability of injury tendon is limited. Tendon stem cells (TSCs) have shown the definitive treatment evidence for tendinopathy and tendon injuries due to their tenogenesis capacity. Aspirin, as the representative of nonsteroidal anti‐inflammatory drugs for its anti‐inflammatory and analgestic actions, has been...

article

Physiological regulation of reactive oxygen species in organisms based on their physicochemical properties

Mei‐Zhou Huang, Jian‐Yong Li

Acta Physiologica > 228 > 1 > n/a - n/a

Oxidative stress is recognized as free radical dyshomeostasis, which has damaging effects on proteins, lipids and DNA. However, during cell differentiation and proliferation and other normal physiological processes, free radicals play a pivotal role in message transmission and are considered important messengers. Organisms maintain free radical homeostasis through a sophisticated regulatory system...

article

Efficacy of verum and sham acupoint catgut embedding for treatment of obesity: Study protocol for a randomized controlled trial

Yu-Mei Zhou, Bing Yan, Wei-Qu Yuan, Hai-Bo Yu, more

Trials > 2019 > 20 > 1 > 1-9

Background Obesity has become a major public health hazard with epidemic proportions, affecting adults, adolescents, and children of both genders. Previous studies have suggested that acupoint catgut embedding (ACE) might be a potential therapeutic approach for obesity. The purpose of this study is to conduct a rigorous and normative trial to determine the efficacy of ACE for obesity. Methods/design...

article

Post‐fire vegetation recovery at forest sites is affected by permafrost degradation in the Da Xing'an Mountains of northern China

Liang Shi, Jeffery P. Dech, Hongyan Liu, Pengwu Zhao, more

Journal of Vegetation Science > 30 > 5 > 940 - 949

Question Vegetation recovery and succession patterns after fire are not completely explained by the interactions of climate, disturbance, and species pool. Site‐specific factors can substantially change vegetation succession. We hypothesize that on sites exposed to fire and surface permafrost degradation, successional trajectories will produce different species assemblages than typical post‐fire...

article

Light (anti)nuclei production in Cu+Cu collisions at $\sqrt{s_{NN}} = 200$ s N N = 200 GeV

Feng-xian Liu, Gang Chen, Zhi-lei Zhe, Dai-mei Zhou, more

The European Physical Journal A > 2019 > 55 > 9 > 1-7

. The production of light (anti)nuclei is investigated using the dynamically constrained phase-space coalescence model based on the final-state hadrons generated by the PACIAE model in Cu+Cu collisions at $\sqrt{s_{\mathrm{NN}}}=200$ s NN = 200 GeV with $\vert\eta\vert < 0.5$ | η | < 0 . 5 and $0 < p_{T} < 8$ 0 < p T < 8 GeV/c. The results show that there...

article

Touschek lifetime study based on the precise bunch-by-bunch BCM system at SSRF

Fang-Zhou Chen, Zhi-Chu Chen, Yi-Mei Zhou, Ning Zhang, more

Nuclear Science and Techniques > 2019 > 30 > 9 > 1-8

Continuous tracking of bunch charges is the key to maintain stable operations in a storage ring in top-up mode. Recently, a precise bunch-by-bunch beam-current measurement (BCM) system has been developed at the Shanghai Synchrotron Radiation Facility. To avoid the influence of longitudinal oscillation on the amplitudes of the sampling points, a method called two-point equilibrium sampling is introduced...

article

Characterizing complication risk from multisite, intermittent transfusions for the treatment of sickle cell disease

Amy Tang, Jane Branscomb, Mei Zhou, Angela Snyder, more

Pediatric Blood & Cancer > 66 > 10 > n/a - n/a

Blood transfusions are indicated for some acute complications of sickle cell disease (SCD). To characterize the SCD population at increased risk of transfusion‐associated complications, Georgia hospital discharge data were used to estimate the frequency of intermittent transfusions and the proportion of patients receiving them at multiple institutions. Ten years of data (2007‐2016) showed almost 19%...

article

TGF‐β1 enhances the activity of acid‐sensing ion channel in rat primary sensory neurons

Chun‐Yu Qiu, Ting‐Ting Liu, Shuang Wei, Yi‐Mei Zhou, more

Journal of Neuroscience Research > 97 > 10 > 1298 - 1305

Transforming growth factor‐β1 (TGF‐β1) is an important member of multifunctional growth factor superfamily. It has been implicated in pain signaling, but little is known about the underlying mechanisms. Herein, we report that TGF‐β1 can exert a sustained enhancing effect on the functional activity of acid‐sensing ion channels (ASICs) in rat dorsal root ganglia (DRG) neurons. Pre‐application of TGF‐β1...

article

Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT‐3 signalling pathway

Yunjiao Wang, Gang He, Hong Tang, Youxing Shi, more

Cell Proliferation > 52 > 4 > n/a - n/a

Objectively Tendinopathy is a common problem in sports medicine which can lead to severe morbidity. Aspirin, as the classical representative of non‐steroidal anti‐inflammatory drugs (NSAIDs) for its anti‐inflammatory and analgesic actions, has been commonly used in treating tendinopathy. While its treatment effects on injury tendon healing are lacking, illuminating the underlying mechanism may provide...

article

LncRNA WWC2-AS1 functions AS a novel competing endogenous RNA in the regulation of FGF2 expression by sponging miR-16 in radiation-induced intestinal fibrosis

Ju-Mei Zhou, Rong Liang, Su-Yu Zhu, Hui Wang, more

BMC Cancer > 2019 > 19 > 1 > 1-10

Background Recently, long non-coding RNAs (lncRNAs) were considered as important gene expression regulators involving various biological processes. In this study, we explored the role of lncRNAs in the pathogenesis of radiation-induced intestinal fibrosis (RIF). Methods LncRNAs were screened by microarray (Human LncRNA Array v3.0, Arraystar, Inc.) and the differentially expressed lncRNAs in RIF...

article

A Fatal Case of Acute Arsenic Poisoning

Ping Lu, Jin‐Qi Ma, Fan Li, Guo‐Hui Xu, more

Journal of Forensic Sciences > 64 > 4 > 1271 - 1273

This manuscript reported a case of fatal arsenic poisoning. A woman with schizophrenia took arsenic‐containing “pills,” which consisted of arsenic trioxide and realgar (arsenic (II) sulfide) and wrapped with gauze. The victim consumed 1.09 and 0.819 g arsenic on two occasions, respectively, with the interval between the two doses of 3 days. The woman died on the sixth day after the first dose without...

article

The Neuroprotective Effect of L-Stepholidine on Methamphetamine-Induced Memory Deficits in Mice

Mei Zhou, Xiaokang Gong, Qin Ru, Qi Xiong, more

Neurotoxicity Research > 2019 > 36 > 2 > 376-386

Repeated methamphetamine (METH) exposure can cause severe neurotoxicity to the central nervous system, and lead to memory deficits. L-Stepholidine (L-SPD) is a structurally identified alkaloid extract of the Chinese herb Stephania intermedia, which elicits dopamine (DA) D1-type receptors partial agonistic activity and D2-type receptors antagonistic activity. In this study, we investigated the effect...

article

Aspirin eugenol ester attenuates oxidative injury of vascular endothelial cells by regulating NOS and Nrf2 signalling pathways

Mei‐Zhou Huang, Ya‐Jun Yang, Xi‐Wang Liu, Zhe Qin, more

British Journal of Pharmacology > 176 > 7 > 906 - 918

Background and Purpose Aspirin eugenol ester (AEE) is a new drug compound synthesized by combining aspirin with eugenol. It was reported to possess anti‐thrombotic, anti‐atherosclerotic, and anti‐oxidative effects. However, its molecular mechanism against oxidative injury is unclear. This study investigated how AEE affected the oxidative injury of vascular endothelial cells in vivo and in vitro....

article

Elevated serum interleukin‐29 levels in patients with Henoch–Schönlein purpura

Tao Chen, Li‐xin Fu, Zai‐pei Guo, Na Cao, more

Australasian Journal of Dermatology > 60 > 1 > e82 - e85

article

Prolonged conservative treatment in patients with recurrent endometrial cancer after primary fertility-sparing therapy: 15-year experience

Yao Wang, Mei Yu, Jia-xin Yang, Dong-yan Cao, more

International Journal of Clinical Oncology > 2019 > 24 > 6 > 712-720

Objective To evaluate the efficacy and prognosis of repeated treatment on patients with recurrent endometrial cancer (EC) after complete remission for primary fertility-preserving therapy. Materials and methods We performed a retrospective study of patients with presumed stage IA endometrial cancer who had recurrence after achieving complete remission by fertility-preserving management at the Department...

article

BAMBI regulates macrophages inducing the differentiation of Treg through the TGF-β pathway in chronic obstructive pulmonary disease

Sheng-Wen Sun, Long Chen, Mei Zhou, Jiang-Hua Wu, more

Respiratory Research > 2019 > 20 > 1 > 1-10

Background Chronic obstructive pulmonary disease (COPD) is characterized by continuous flow limitation and the immune system including macrophages and regulatory T lymphocytes (Tregs) is involved in COPD pathogenesis. In our previous study, we investigated that TGF-β/BAMBI pathway was associated with COPD by regulating the balance of Th17/Treg. However, the role of bone morphogenetic protein and activin...

article

Research Progress in MRI of the Visual Pathway in Diabetic Retinopathy

Yu-min Li, Hong-mei Zhou, Xiang-yang Xu, He-shui Shi

Current Medical Science > 2018 > 38 > 6 > 968-975

Summary With an increasing incidence, diabetic retinopathy is one of the most important complications of diabetes mellitus (DM) and is also known as one of the major reasons of adult acquired blindness. It is widely accepted that the visual impairment of diabetic patients results from retinal microvascular changes. However, recent clinical experimental and neuroimaging studies suggest that the visual...

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INFONA - science communication portal

Search results for: Mei Zhou

Resveratrol attenuates methamphetamine‐induced memory impairment via inhibition of oxidative stress and apoptosis in mice

Characterisation of a novel peptide, Brevinin‐1H, from the skin secretion of Amolops hainanensis and rational design of several analogues

Factors associated with core competencies of emergency‐room nurses in tertiary hospitals in China

Aspirin promotes tenogenic differentiation of tendon stem cells and facilitates tendinopathy healing through regulating the GDF7/Smad1/5 signaling pathway

Physiological regulation of reactive oxygen species in organisms based on their physicochemical properties

Efficacy of verum and sham acupoint catgut embedding for treatment of obesity: Study protocol for a randomized controlled trial

Post‐fire vegetation recovery at forest sites is affected by permafrost degradation in the Da Xing'an Mountains of northern China

Light (anti)nuclei production in Cu+Cu collisions at $\sqrt{s_{NN}} = 200$ s N N = 200 GeV

Touschek lifetime study based on the precise bunch-by-bunch BCM system at SSRF

Characterizing complication risk from multisite, intermittent transfusions for the treatment of sickle cell disease

TGF‐β1 enhances the activity of acid‐sensing ion channel in rat primary sensory neurons

Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT‐3 signalling pathway

LncRNA WWC2-AS1 functions AS a novel competing endogenous RNA in the regulation of FGF2 expression by sponging miR-16 in radiation-induced intestinal fibrosis

A Fatal Case of Acute Arsenic Poisoning

The Neuroprotective Effect of L-Stepholidine on Methamphetamine-Induced Memory Deficits in Mice

Aspirin eugenol ester attenuates oxidative injury of vascular endothelial cells by regulating NOS and Nrf2 signalling pathways

Elevated serum interleukin‐29 levels in patients with Henoch–Schönlein purpura

Prolonged conservative treatment in patients with recurrent endometrial cancer after primary fertility-sparing therapy: 15-year experience

BAMBI regulates macrophages inducing the differentiation of Treg through the TGF-β pathway in chronic obstructive pulmonary disease

Research Progress in MRI of the Visual Pathway in Diabetic Retinopathy

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