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Introduction & Aims
Haemophilic arthropathy (HA) is a major complication in patients with haemophilia (PWH), but the study of age‐specific prevalence and severity of HA is very limited in Asian countries.
Materials & Methods
This study retrospectively reviewed 146 severe‐ and moderate‐type Taiwanese PWH aged 4–73 years, with roentgenograms of elbows, knees and ankles and calculated Pettersson...
Summary. This study compared secondary prophylaxis treatment with on‐demand treatment for severe haemophilia A in Taiwan. Fifty patients from one medical centre were evaluated over a 5‐year period. Differences in annual bleed rates and factor VIII (FVIII) utilization were assessed between patients receiving secondary prophylaxis and patients receiving FVIII concentrates on‐demand. Results were then...
Summary. Haemophilia A (HA) is an X‐linked bleeding disorder caused by mutations in the factor VIII (FVIII) gene. Identification of these mutations is becoming increasingly important in a variety of clinical settings. The purpose of this report is to describe our experience of FVIII gene mutation analysis in the largest cohort of patients in Taiwan including the discovery of 21 novel mutations. We...
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