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The present study used functional and electrophysiological approaches to investigate the mechanisms by which warifteine, a bisbenzylisoquinoline alkaloid isolated from Cissampelos sympodialis Eichl., causes vasorelaxation of the rat thoracic aorta.Warifteine (1 pmol/L–10 μmol/L) induced concentration‐dependent relaxation (pD2 = 9.40 ± 0.06; n = 5) of endothelium‐intact aortic rings precontracted with...