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A strategy for controlling a fed‐batch Escherichia coli culture is described to maintain the culture at the boundary between oxidative and oxido‐fermentative regimes. A nonlinear predictive controller is designed to regulate the acetate concentration, constraining the feed rate to follow an optimal reference profile which maximizes the biomass growth. For the sake of simplicity and efficiency, the...
This paper presents a nonlinear predictive control (NMPC) strategy applied to the continuous microalgae cultivation process in a closed photobioreactor. The photo-bioreactor system is programmed to operate in a constant biomass density mode, in order to maintain the culture at the optimal population density and sustain high biomass production levels. This objective is achieved by regulating the biomass...
This paper presents a nonlinear predictive control strategy for maximizing the biomass growth in fed-batch cultures of E. Coli. This objective is achieved by regulating the acetate concentration at a low measurable value, while tracking (in a compromising way) an optimal glucose feed-rate trajectory determined off-line. Robustness with respect to model uncertainties is improved by taking system/model...
This paper proposes the design of a nonlinear model predictive control (NMPC) scheme for the regulation of the acetic acid concentration (leading to the biomass growth maximization) during high cell density fed-batch cultures of Escherichia coli. For NMPC purposes, an unstructured model for the growth is first derived with respect to the major metabolic pathways: oxidative growth on glucose, fermentative...
This paper proposes the design of a nonlinear model predictive control (NMPC) scheme for the regulation of the acetic acid concentration (leading to the biomass growth maximization) during high cell density fed-batch cultures of Escherichia coli. For NMPC purposes, an unstructured model for the growth is first derived with respect to the major metabolic pathways: oxidative growth on glucose, fermentative...
This paper relates recent advances in the design of feedback laws for the 3D movement of an Eel-like robot. Such a robot is under construction in the context of a national French robotic project. The proposed feedback enables the tracking of a desired 3D position of the Eel head as well as the stabilization of the rolling angle. A velocity controller is also proposed. The controller is tested on a...
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