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The HPA-1a (Leu 33 ) polymorphism of platelet integrin αIIbβ3 is the target of alloantibodies in 70–80% cases of neonatal alloimmune thrombocytopenia (NAIT) in Caucasians and reliable detection of these antibodies is essential for appropriate clinical management. However, the ability to detect such antibodies is highly variable between laboratories and, in a number of clinical cases where...
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