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Background Progressive lung involvement in Filamin A (FLNA)-related cerebral periventricular nodular heterotopia (PVNH) has been reported in a limited number of cases. Case presentation We report a new pathogenic FLNA gene variant (c.7391_7403del; p.Val2464Alafs*5) in a male infant who developed progressive lung disease with emphysematous lesions and interstitial involvement. Following lobar resection,...
Background Hemodynamic changes during laparoscopy have not been well defined in very young children. In this study, intraoperative monitoring of hemodynamic parameters and oxygenation was evaluated during laparoscopy in infants weighing < 10 kg. Patients and methods Thirty infants (5.07 ± 2.51 kg), undergoing laparoscopy (LAP Group, n = 15) or open surgery (Open Group, n = 15), were enrolled...
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