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Background/Aims: Evidence that the geno/subtype of hepatitis C virus (HCV) is predictive of the response to initerferon-α therapy suggests that typing methods are clinical useful. In the present study, HCV isolates obtained from 74 patients with chronic hepatitis C were used to evaluate three genotyping and two serotyping assays.Methods: The reverse hybridization assay and the DNA immunoassay are...
Background/Aims: Several strains of the hepatitis C virus exist; distinct genotypes and subtypes can be identified by sequence comparison of the viral genomes. Recent evidence that the genotype/subtype of hepatitis C virus may infuence the clinical course of chronic hepatitis C and the response to interferon-a therapy for this disease suggests that methods to identify the genotype may become clinically...
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