Search results for: Shuai Zhu

Items from 1 to 20 out of 59 results

article

Phosphoric Acid‐Catalyzed Enantioselective Synthesis of Axially Chiral Anthrone‐based Compounds

Shi‐Jiang He, Shuai Zhu, Sheng‐Qi Qiu, Wei‐Yi Ding, more

Angewandte Chemie International Edition > 62 > 1 > n/a - n/a

Anthrones and analogues are structural cores shared by diverse pharmacologically active natural and synthetic compounds. The sp²‐rich nature imposes inherent obstruction to introduce stereogenic element onto the tricyclic aromatic backbone. In our pursuit to expand the chemical space of axial chirality, a novel type of axially chiral anthrone‐derived skeleton was discovered. This work establishes...

article

Phosphoric Acid‐Catalyzed Enantioselective Synthesis of Axially Chiral Anthrone‐based Compounds

Shi‐Jiang He, Shuai Zhu, Sheng‐Qi Qiu, Wei‐Yi Ding, more

Angewandte Chemie > 135 > 1 > n/a - n/a

article

Adaptive event‐triggered asynchronous fault‐tolerant control for stochastic systems with multiple‐types of failures

Shuai Zhu, Jian‐Ning Li, Ai‐Min Wang

International Journal of Adaptive Control and Signal Processing > 36 > 10 > 2401 - 2418

This article studies a kind of asynchronous fault‐tolerant control problem for stochastic systems (Markov jump systems, MJSs) with multiple‐types of actuator failures. Both the loss of effectiveness and stuck fault of actuator are taken into consideration in a unified actuator failures model. The asynchronization phenomenon between the controller and the original system is described by a hidden Markov...

article

Palladium/TY‐Phos‐Catalyzed Asymmetric Intermolecular α‐Arylation of Aldehydes with Aryl Bromides

Zhangjin Pan, Wenbo Li, Shuai Zhu, Feng Liu, more

Angewandte Chemie > 133 > 34 > 18690 - 18694

Despite much progress has been made in the asymmetric α‐arylation reactions of cyclic ketones, lactones and lactams, the enantioselective α‐arylation of acyclic carbonyl compounds lagged much behind due to the in situ generated Z/E‐enolate intermediates leading to opposite enantiomers. Especially, the asymmetric α‐arylation of acyclic aldehydes is a long‐standing challenge, because of the highest...

article

Palladium/TY‐Phos‐Catalyzed Asymmetric Intermolecular α‐Arylation of Aldehydes with Aryl Bromides

Zhangjin Pan, Wenbo Li, Shuai Zhu, Feng Liu, more

Angewandte Chemie International Edition > 60 > 34 > 18542 - 18546

article

Candidemia indicates poor outcome in patients with infected pancreatic necrosis

Caihong Ning, Shuai Zhu, Qin Wei, Zhiyong Liu, more

Mycoses > 64 > 6 > 684 - 690

Background Intra‐abdominal fungal infection (AFI) and candidemia are common in patients with acute pancreatitis (AP), but with limited and conflicting reports on their clinical impacts. This study aims to evaluate the clinical impacts of AFI and candidemia in infected pancreatic necrosis (IPN). Methods A single‐centre, prospective cohort including 235 consecutive patients with IPN between January...

article

The NPR1‐WRKY46‐WRKY6 signaling cascade mediates probenazole/salicylic acid‐elicited leaf senescence in Arabidopsis thaliana

Dingyu Zhang, Zheng Zhu, Jiong Gao, Xin Zhou, more

Journal of Integrative Plant Biology > 63 > 5 > 924 - 936

Endogenous salicylic acid (SA) regulates leaf senescence, but the underlying mechanism remains largely unexplored. The exogenous application of SA to living plants is not efficient for inducing leaf senescence. By taking advantage of probenazole (PBZ)‐induced biosynthesis of endogenous SA, we previously established a chemical inducible leaf senescence system that depends on SA biosynthesis and its...

article

Fully automated identification and quantification of five polar pesticides in groundwater by isotope dilution‐online solid phase extraction coupled with high‐performance liquid chromatography‐quadrupole Orbitrap high‐resolution mass spectrometry

Xiang‐ting Tu, Han‐xiao Zhou, Shu‐ting Wang, Feng Guo, more

Journal of Mass Spectrometry > 56 > 4 > n/a - n/a

A fully automated method for identification and quantification of five polar pesticides in groundwater by isotope dilution‐online solid‐phase extraction (SPE) coupled with high‐performance liquid chromatography‐quadrupole Orbitrap high‐resolution mass spectrometry was developed. After one step of filtration, an aliquot of a 7.5‐ml water sample was automatedly preconcentrated and purified on a turbulent...

article

Numerical implementation of nonlinear system of fractional Volterra integral–differential equations by Legendre wavelet method and error estimation

Lijing Shen, Shuai Zhu, Bingcheng Liu, Zirui Zhang, more

Numerical Methods for Partial Differential Equations > 37 > 2 > 1344 - 1360

In the current study, a numerical scheme for solving the nonlinear system of fractional Volterra integro‐differential equations via Legendre wavelet is proposed. The Legendre wavelet operational matrix of fractional integration is derived and utilized to alter the main system to a system of algebraic equations. In addition, the error estimate of the original system is investigated in detail. Lastly,...

article

Analytical solutions of heat storage and heat transfer performance of parallel‐plate regenerators in Stirling cycle

Huanguang Wang, Yunhao Bao, Yuming Tang, Meng Liu, more

International Journal of Energy Research > 45 > 2 > 3327 - 3342

Parallel‐plate regenerators (PPR), with flow resistance lower than traditional wire‐mesh regenerators, can improve the thermal efficiency of Stirling engines (SEs). However, as working frequency or plate thickness increase, the heat cannot penetrate into the plate effectively, resulting only the surface part of the plates to have substantial temperature variation, while the internal part fails to...

article

Involvement of SIRT3‐GSK3β deacetylation pathway in the effects of maternal diabetes on oocyte meiosis

Yongan Xin, Yifei Jin, Juan Ge, Zhenyue Huang, more

Cell Proliferation > 54 > 1 > n/a - n/a

Objectives It has been widely reported that maternal diabetes impairs oocyte quality. However, the responsible mechanisms remain to be explored. In the present study, we focused on whether SIRT3‐GSK3β pathway mediates the meiotic defects in oocytes from diabetic mice. Materials and methods GSK3β functions in mouse oocyte meiosis were first detected by targeted siRNA knockdown. Spindle assembly...

article

Design and Synthesis of TY‐Phos and Application in Palladium‐Catalyzed Enantioselective Fluoroarylation of gem‐Difluoroalkenes

Tao‐Yan Lin, Zhangjin Pan, Youshao Tu, Shuai Zhu, more

Angewandte Chemie International Edition > 59 > 51 > 22957 - 22962

The first example of highly enantioselective fluoroarylation of gem‐difluoroalkenes with aryl halides is presented by using a new chiral sulfinamide phosphine (Sadphos) type ligand TY‐Phos. N‐Me‐TY‐Phos can be easily synthesized on a gram scale from readily available starting materials in three steps. Salient features of this work including readily available starting materials, good yields, high enantioselectivities...

article

Design and Synthesis of TY‐Phos and Application in Palladium‐Catalyzed Enantioselective Fluoroarylation of gem‐Difluoroalkenes

Tao‐Yan Lin, Zhangjin Pan, Youshao Tu, Shuai Zhu, more

Angewandte Chemie > 132 > 51 > 23157 - 23162

article

Meiotic block with roscovitine improves competence of porcine oocytes by fine‐tuning activities of different cyclin‐dependent kinases

Shuai Zhu, Ying‐Jun Jia, Liu‐Zhu Pan, Shuai Gong, more

Journal of Cellular Physiology > 235 > 10 > 7530 - 7540

Successful use of oocytes from small follicles (SFs) is of great importance for animal embryo production and human in vitro fertilization with reduced hormone‐related side effects. How in vitro meiotic arrest maintenance (MAM) increases the competence of oocytes is not clear. In this study, pig oocytes recovered from SF of 1–2 mm and medium‐follicles (MF) of 3–6 mm in diameter from abattoir ovaries...

article

Inhibition of microRNA‐199a‐5p ameliorates oxygen‐glucose deprivation/reoxygenation‐induced apoptosis and oxidative stress in HT22 neurons by targeting Brg1 to activate Nrf2/HO‐1 signalling

Feng Li, Jing Liang, Hua Tong, Shuai Zhu, more

Clinical and Experimental Pharmacology and Physiology > 47 > 6 > 1020 - 1029

MicroRNAs (miRNAs) have emerged as critical regulators of neuronal survival during cerebral ischaemia/reperfusion injury. Accumulating evidence has shown that miR‐199a‐5p plays a crucial role in regulating apoptosis and survival in various cell types. However, whether miR‐199a is involved in regulating neuronal survival during cerebral ischaemia/reperfusion injury remains unknown. In this study, we...

article

Biofiltration and disinfection codetermine the bacterial antibiotic resistome in drinking water: A review and meta-analysis

Kun Wan, Wenfang Lin, Shuai Zhu, Shenghua Zhang, more

Frontiers of Environmental Science & Engineering > 2020 > 14 > 1 > 1-12

The bacterial antibiotic resistome (BAR) is one of the most serious contemporary medical challenges. The BAR problem in drinking water is receiving growing attention. In this study, we focused on the distribution, changes, and health risks of the BAR throughout the drinking water treatment system. We extracted the antibiotic resistance gene (ARG) data from recent publications and analyzed ARG profiles...

article

Copper‐Catalyzed C–C Bond Cleavage/Double Cyclization of α‐Ketoamides with o‐Phenylene Diamines: Synthesis of Benzimidazo[1,2‐c]quinazolin‐6‐ones

Liang‐Hua Zou, Cheng Yan, Kai Shi, Liang Su, more

European Journal of Organic Chemistry > 2019 > 47 > 7725 - 7729

A highly regioselective C–C bond cleavage/double cyclization of α‐ketoamides with o‐phenylene diamines has been developed for the synthesis of benzimidazo[1,2‐c]quinazolin‐6‐ones. Two new C–N and one new C=N bonds are simultaneously formed in the reaction, providing the gateway to access these fused heterocyclic scaffolds via copper catalysis under air atmosphere. This new protocol provides a novel...

article

CFD-PBM Simulation and PIV Measurement of Liquid–Liquid Flow in a Continuous Stirring Settler

Xu-huan Guo, Ting-an Zhang, Qiu-yue Zhao, Zi-mu Zhang, more

JOM > 2019 > 71 > 12 > 4500-4508

The mixer settler is widely employed in the extraction and recycling of battery materials. The improvement of the separation efficiency is one of the most important issues. In order to investigate the effect of agitating speed on the flow characteristics and settling performance, both computational fluid dynamics coupled population balance model simulations and experiments with particle image velocimetry...

article

Simulation and experimental analysis of autoclave co-curing CFRP hat-stiffened panels with silicone airbag mandrels

Pingping Xie, Shuai Zhu, Yiyu Shao, Wenfei Peng, more

Iranian Polymer Journal > 2019 > 28 > 6 > 505-514

The inflatable mandrel is easy to be broken and wrinkled during the co-curing process of the hat-stiffened wall panels. The metal mandrel is difficult to demold, the water-soluble mandrel is easy to be broken, and the pressure transmission uniformity of the silicone mandrel with preformed apertures is difficult to ensure during the manufacturing process. To solve these problems, a new process for...

article

Recent Advances in Direct Functionalization of Quinones

Yijun Wang, Shuai Zhu, Liang‐Hua Zou

European Journal of Organic Chemistry > 2019 > 12 > 2179 - 2201

Developing methods for the direct functionalization of quinones for assembly of highly functionalized quinones or bioactive natural products is an essential topic in the field of direct C–H functionalization. Quinone units are key motifs in many bioactive compounds and materials, and many innovative methods have been elaborated for the generation of these units. A major part of the established synthetic...

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INFONA - science communication portal

Search results for: Shuai Zhu

Phosphoric Acid‐Catalyzed Enantioselective Synthesis of Axially Chiral Anthrone‐based Compounds

Phosphoric Acid‐Catalyzed Enantioselective Synthesis of Axially Chiral Anthrone‐based Compounds

Adaptive event‐triggered asynchronous fault‐tolerant control for stochastic systems with multiple‐types of failures

Palladium/TY‐Phos‐Catalyzed Asymmetric Intermolecular α‐Arylation of Aldehydes with Aryl Bromides

Palladium/TY‐Phos‐Catalyzed Asymmetric Intermolecular α‐Arylation of Aldehydes with Aryl Bromides

Candidemia indicates poor outcome in patients with infected pancreatic necrosis

The NPR1‐WRKY46‐WRKY6 signaling cascade mediates probenazole/salicylic acid‐elicited leaf senescence in Arabidopsis thaliana

Fully automated identification and quantification of five polar pesticides in groundwater by isotope dilution‐online solid phase extraction coupled with high‐performance liquid chromatography‐quadrupole Orbitrap high‐resolution mass spectrometry

Numerical implementation of nonlinear system of fractional Volterra integral–differential equations by Legendre wavelet method and error estimation

Analytical solutions of heat storage and heat transfer performance of parallel‐plate regenerators in Stirling cycle

Involvement of SIRT3‐GSK3β deacetylation pathway in the effects of maternal diabetes on oocyte meiosis

Design and Synthesis of TY‐Phos and Application in Palladium‐Catalyzed Enantioselective Fluoroarylation of gem‐Difluoroalkenes

Design and Synthesis of TY‐Phos and Application in Palladium‐Catalyzed Enantioselective Fluoroarylation of gem‐Difluoroalkenes

Meiotic block with roscovitine improves competence of porcine oocytes by fine‐tuning activities of different cyclin‐dependent kinases

Inhibition of microRNA‐199a‐5p ameliorates oxygen‐glucose deprivation/reoxygenation‐induced apoptosis and oxidative stress in HT22 neurons by targeting Brg1 to activate Nrf2/HO‐1 signalling

Biofiltration and disinfection codetermine the bacterial antibiotic resistome in drinking water: A review and meta-analysis

Copper‐Catalyzed C–C Bond Cleavage/Double Cyclization of α‐Ketoamides with o‐Phenylene Diamines: Synthesis of Benzimidazo[1,2‐c]quinazolin‐6‐ones

CFD-PBM Simulation and PIV Measurement of Liquid–Liquid Flow in a Continuous Stirring Settler

Simulation and experimental analysis of autoclave co-curing CFRP hat-stiffened panels with silicone airbag mandrels

Recent Advances in Direct Functionalization of Quinones

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