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Cell cytoskeleton makes profound changes during apoptosis including the organization of an Apoptotic Microtubule Network (AMN). AMN forms a cortical structure which plays an important role in preserving plasma membrane integrity during apoptosis. Here, we examined the cytoskeleton rearrangements during apoptosis induced by camptothecin (CPT), a topoisomerase I inhibitor, in human H460 and porcine...
Relevant progress has been done, within the Robotics field, in mechanical systems, actuators, control and planning. This fact, allows a wide application of industrial robots, where manipulator arms, Cartesian robots, etc., widely outcomes human capacity. However, the achievement of a robust and reliable autonomous mobile robot, with ability to evolve and accomplish general tasks in unconstrained...
This paper describes a global database recorder architecture following a multi agent system philosophy to provide a specific global database information service. The global database stores relevant vehicles information, related to trips data and risky situations occurred. Trip information and risky situations details (stored previously on vehicle's local databases) are gathered together and used to...
Apoptotic microtubule network (AMN) is organized during apoptosis, forming a cortical structure beneath the plasma membrane which plays a critical role in preserving cell morphology and plasma membrane integrity. The aim of this study was to examine the effect of cold/warming exposure on apoptotic microtubules and plasma membrane integrity during the execution phase of apoptosis. We demonstrated in...
The present paper describes the framework and components of an instrumented vehicle for driver assistance and safety. The experimental platform is based on the use of an on-board computer vision system to capture the traffic signs, and on a multiple of electronic components to capture the vehicle state and identify drivers. The hardware architecture is designed with the purpose of making the deployment...
This paper describes the overall framework and components of an experimental platform for driver behavior monitoring based on driver's traffic violation records. This platform is composed of two separate subsystems: a driver assistance system based on road sign detection and recognition, and a traffic violation recording unit in which the vehicle is involved. The system provides drivers with their...
Mitochondrial DNA mutations are an important cause of human disease for which there is no effective treatment. Myoclonic epilepsy with ragged-red fibers (MERRF) is a mitochondrial disease usually caused by point mutations in transfer RNA genes encoded by mitochondrial DNA. The most common mutation associated with MERRF syndrome, m.8344A > G in the gene MT-TK, which encodes transfer RNALysine, affects...
The present paper presents an in-vehicle system for traffic violation alert and management. The system hardware consists of a combination of an on-board computer vision system for traffic sign detection and recognition with a data recorder device for traffic violation alert and management. At present, traffic violations are only focused on three signs: namely speed limit, stop sign, and forbidden...
Microtubule cytoskeleton is reformed during apoptosis, forming a cortical structure beneath plasma membrane, which plays an important role in preserving cell morphology and plasma membrane integrity. However, the maintenance of the apoptotic microtubule network (AMN) during apoptosis is not understood. In the present study, we examined apoptosis induced by camptothecin (CPT), a topoisomerase I inhibitor,...
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