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To improve the distinguishing of vital protein, vertex-cover-parameter (VCP) is proposed to scale a node's status in a bionetwork. To keep away from the NP-hard which probable met in the acquisition of VCP, a parameterized algorithm is used to compress the size of the network to get its kernel, and then an exact or non-exact algorithm is used to solve the kernel and obtain the VCP of each node. In...
For the low recognition degree of essential protein based on topological parameter, the correlation between the essentiality of proteins and their main topological parameters is analyzed and the nature of the essentiality-judgment ability of the parameters is explored firstly. Then, the mutual information of essential node these parameters contain is brought out in virtue of their correlation, based...
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