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We report the first demonstration of single nanoparticle detection and size measurement in water using mode splitting in high-Q optical resonators. We achieved detecting and measuring polystyrene individual nanoparticles down to 75 nm in radius.
We show that adsorption of individual viruses and nanoparticles leads to discrete changes in the mode splitting spectra of a whispering-gallery-mode (WGM) microcavity, which enables a single nanoparticle spectrometry scheme to measure each particle.
We demonstrate detection and sizing of single nanoparticles down to 30 nm by monitoring the mode splitting induced by a nanoparticle in an ultra-high quality factor (UHQ) microtoroid. Theory and methods are discussed.
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