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In proteins, functional divergence involves mutations that modify structure and dynamics. Here we provide experimental evidence for an evolutionary mechanism driven solely by long-range dynamic motions without significant backbone adjustments, catalytic group rearrangements, or changes in subunit assembly. Crystallographic structures were determined for several reconstructed ancestral proteins belonging...
Compressed Sensing (CS) is a novel approach of reconstructing a sparse signal much below the significant Nyquist rate of sampling. Due to the fact that ECG signals can be well approximated by the few linear combinations of wavelet basis, this work introduces a comparison of the reconstructed 10 ECG signals based on different wavelet families, by evaluating the performance measures as MSE (Mean Square...
Compressed Sensing (CS) is a novel approach of reconstructing a sparse signal much below the significant Nyquist rate of sampling. Due to the fact that ECG signals can be well approximated by the few linear combinations of wavelet basis, this work introduces a comparison of the reconstructed ECG signal based on different wavelet families, by evaluating the performance measures as MSE (Mean Square...
In this paper, we present novel approach for text extraction. In computer vision r esearch area, text is very important in images. Here we use edge based extraction of text using ISEF (infinit e symmetrical edge filter). ISEF is optimal edge det ector which gives accurate results for text in imag es. Text extraction involves detection, localization, tracking and enhancement. Large numbers of te chnique...
Background The stability of Clostridium difficile toxins is an important factor in determining the accuracy of the enzyme immunoassay (EIA). The Centers for Disease Control has stated that C. difficile toxins may become undetectable in unrefrigerated stool specimens within 2 h after collection. Purpose The purpose of our study was to determine how the unrefrigerated handling time of human fecal...
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