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Objective: to evaluate changes in vasomotor endothelium function and elastic properties of the brachial artery in postmenopausal women beginning hormone replacement therapy (HRT) with Climen(R), a 28-day sequential therapy combining estradiol valerate (E2V) 2 mg/day D1-D21 with cyproterone acetate (CPA) 1 mg/day D12-D22, followed by a 7-day treatment-free interval. Methods: Thirty-one women with natural...
To compare the metabolic effects of two different administration routes of estrogen associated with cyproterone acetate (CPA) in young women.Randomized and prospective study.University medical and research center.Sixty-five premenopausal young women with clinical hyperandrogenism.A high dose of CPA was administered, associated with either transdermal (group T) or oral (group O) 17β-E2.Glucose tolerance,...
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