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To determine the nature of intracellular Mg 2+ stores and Mg 2+ release mechanisms in differentiated PC12 cells, Mg 2+ and Ca 2+ mobilizations were measured simultaneously in living cells with KMG-104, a fluorescent Mg 2+ indicator, and fura-2, respectively. Treatment with the mitochondrial uncoupler, carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone (FCCP),...
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