Search results for: Andrew M. Crean

Items from 1 to 20 out of 41 results

article

Cardiac MRI and radionuclide ventriculography for measurement of left ventricular ejection fraction in ICD candidates

Vamshi K. Kotha, Djeven P. Deva, Kim A. Connelly, Michael R. Freeman, more

Magnetic Resonance Imaging > 2018 > 52 > C > 69-74

Current guidelines provide left ventricular ejection fraction (LVEF) criterion for use of implantable cardioverter defibrillators (ICD) but do not specify which modality to use for measurement. We compared LVEF measurements by radionuclide ventriculography (RNV) vs cardiac MRI (CMR) in ICD candidates to assess impact on clinical decision making.This single-centre study included 124 consecutive patients...

article

Noninvasive hematocrit assessment for cardiovascular magnetic resonance extracellular volume quantification using a point-of-care device and synthetic derivation

Sean Robison, Gauri Rani Karur, Rachel M. Wald, Paaladinesh Thavendiranathan, more

Journal of Cardiovascular Magnetic Resonance > 2018 > 20 > 1 > 1-9

Background Calculation of cardiovascular magnetic resonance (CMR) extracellular volume (ECV) requires input of hematocrit, which may not be readily available. The purpose of this study was to evaluate the diagnostic accuracy of ECV calculated using various noninvasive measures of hematocrit compared to ECV calculated with input of laboratory hematocrit as the reference standard. Methods One hundred...

article

Phenotype, management and predictors of outcome in a large cohort of adult congenital heart disease patients with heart failure

Alexander Van De Bruaene, Edward J. Hickey, Adrienne H. Kovacs, Andrew M. Crean, more

International Journal of Cardiology > 2018 > 252 > C > 80-87

Although heart failure (HF) is the leading cause of premature death in adult congenital heart disease (ACHD), little population-specific data exist. This study reports early experience from a dedicated, sub-specialty adult congenital heart disease-heart failure (ACHD-HF) clinic, aiming to identify risk factors for adverse outcome.Between 2012 and 2015, 126 patients (57% male) attended the ACHD-HF...

article

The Role of Radionuclide Imaging in Congenital Heart Disease

Andrew M. Crean, Fozia Ahmed, Manish Motwani

Current Cardiovascular Imaging Reports > 2017 > 10 > 11 > 1-15

Purpose of Review Congenital heart disease is a growing healthcare issue since the majority of children who underwent surgical repair are now surviving into adult life. However, these patients are generally fixed but not cured and many will go on to develop significant morbidity as adults. The purpose of this review is to discuss the utility of radionuclide imaging in the management of these patients...

article

Patient Selection Process for the Harmony Transcatheter Pulmonary Valve Early Feasibility Study

Matthew J. Gillespie, Lee N. Benson, Lisa Bergersen, Emile A. Bacha, more

The American Journal of Cardiology > 2017 > 120 > 8 > 1387-1392

This early feasibility study was designed to obtain in vivo data to confirm assumptions on device loading conditions of the Medtronic Harmony transcatheter pulmonary valve (TPV). Secondary objectives included procedural feasibility, safety, and valve performance. The Harmony TPV was developed for nonsurgical pulmonary valve replacement in non–right ventricle-pulmonary artery conduit patients. The...

article

Harmony Feasibility Trial

Lisa Bergersen, Lee N. Benson, Matthew J. Gillespie, Sharon L. Cheatham, more

JACC: Cardiovascular Interventions > 2017 > 10 > 17 > 1763-1773

This study sought to obtain in vivo data to confirm assumptions on device loading conditions and assess procedural feasibility, safety, and valve performance.The Harmony transcatheter pulmonary valve (Medtronic, Minneapolis, Minnesota) was designed for patients with severe pulmonary regurgitation who require pulmonary valve replacement.Three sites participated in this first Food and Drug Administration–approved...

article

Management of Bilateral Axillary Aneurysms, Threatened Limb, and Diffuse Vasculopathy in a Patient With ACTA2 Mutation

Michelle Keir, Wissam Al-Jundi, Maral Ouzounian, Andrew M. Crean, more

Canadian Journal of Cardiology > 2017 > 33 > 4 > 554.e1-554.e3

We describe the case of a 36-year-old man with bilateral axillary artery aneurysms and a threatened upper limb. We postulate that his aneurysms and diffuse vasculopathy resulted from a missense mutation identified in his ACTA2 gene known to be highly pathogenic. The risk factors and sequelae of axillary aneurysms are reviewed, with a focus on their surgical management and the effect of ACTA2 mutations...

article

Proving the innocence of a “malignant” coronary artery: Calling dobutamine stress CT for the defence!

Michelle Keir, Danna Spears, Christopher Caldarone, Andrew M. Crean

Journal of Cardiovascular Computed Tomography > 2017 > 11 > 1 > 68-69

article

The IMPACT-CABG trial: A multicenter, randomized clinical trial of CD133+ stem cell therapy during coronary artery bypass grafting for ischemic cardiomyopathy

Nicolas Noiseux, Samer Mansour, Richard Weisel, Louis-Mathieu Stevens, more

The Journal of Thoracic and Cardiovascular Surgery > 2016 > 152 > 6 > 1582-1588.e2

The IMPACT-CABG trial is the first North American multicenter phase II randomized study of intramyocardial delivery of autologous CD133⁺ stem cells in patients with chronic ischemic cardiomyopathy undergoing coronary artery bypass grafting. The primary objective was to demonstrate safety, including freedom from major adverse cardiac events. The secondary objective was to evaluate feasibility of same-day...

article

Uric acid bladder stones in congenital cyanotic heart disease

Ashish Shah, Michelle Keir, Robin Ducas, Andrew M Crean

The Lancet > 2016 > 388 > 10054 > 1921

article

Does a dedicated subspecialty ACHD coronary clinic result in greater consistency in approach and reduced loss to follow-up? An evaluation of the first 3years of the Toronto Congenital Coronary Clinic for Adults

Michelle Keir, Rachel M. Wald, S. Lucy Roche, Erwin N. Oechslin, more

Progress in Pediatric Cardiology > 2015 > 39 > 2 Part B > 145-150

article

Endorsed by the Society of Pediatric Radiology (SPR) and the North American Society of Cardiac Imaging (NASCI)

B. Kelly Han, Cynthia K. Rigsby, Jonathon Leipsic, Dianna Bardo, more

Journal of Cardiovascular Computed Tomography > 2015 > 9 > 6 > 493-513

article

Endorsed by the Society of Pediatric Radiology (SPR) and the North American Society of Cardiac Imaging (NASCI)

B. Kelly Han, Cynthia K. Rigsby, Anthony Hlavacek, Jonathon Leipsic, more

Journal of Cardiovascular Computed Tomography > 2015 > 9 > 6 > 475-492

This is an expert consensus document created to provide information about the current use of cardiovascular computed tomography (CT) in patients of all ages with proven or suspected congenital heart disease (CHD). The discussion and recommendations are based on available literature and the judgment of a diverse group of subspecialists with extensive experience in the use of CT imaging in CHD. The...

article

Percutaneous Correction of Right Superior Vena Cava to Left Atrium

Andrew R. Leventhal, Ashish H. Shah, Andrew M. Crean, Mark Osten, more

JACC: Cardiovascular Interventions > 2015 > 8 > 13 > e221-e222

article

Outcomes of Aortic Valve-Sparing Operations in Marfan Syndrome

Tirone E. David, Carolyn M. David, Cedric Manlhiot, Jack Colman, more

Journal of the American College of Cardiology > 2015 > 66 > 13 > 1445-1453

In many cardiac units, aortic valve-sparing operations have become the preferred surgical procedure to treat aortic root aneurysm in patients with Marfan syndrome, based on relatively short-term outcomes.This study examined the long-term outcomes of aortic valve-sparing operations in patients with Marfan syndrome.All patients with Marfan syndrome operated on for aortic root aneurysm from 1988 through...

article

Use of Cardiac Magnetic Resonance Imaging Based Measurements of Inferior Vena Cava Cross-Sectional Area in the Diagnosis of Pericardial Constriction

Kate Hanneman, Paaladinesh Thavendiranathan, Elsie T. Nguyen, Hadas Moshonov, more

Canadian Association of Radiologists Journal > 2015 > 66 > 3 > 231-237

To evaluate the value of cardiac magnetic resonance imaging (MRI)–based measurements of inferior vena cava (IVC) cross-sectional area in the diagnosis of pericardial constriction.Patients who had undergone cardiac MRI for evaluation of clinically suspected pericardial constriction were identified retrospectively. The diagnosis of pericardial constriction was established by clinical history, echocardiography,...

article

Significance of Late Gadolinium Enhancement at Right Ventricular Attachment to Ventricular Septum in Patients With Hypertrophic Cardiomyopathy

Raymond H. Chan, Barry J. Maron, Iacopo Olivotto, Gabriele E. Assenza, more

The American Journal of Cardiology > 2015 > 116 > 3 > 436-441

Cardiovascular magnetic resonance (CMR) with extensive late gadolinium enhancement (LGE) is a novel marker for increased risk for sudden death (SD) in patients with hypertrophic cardiomyopathy (HC). Small focal areas of LGE confined to the region of right ventricular (RV) insertion to ventricular septum (VS) have emerged as a frequent and highly visible CMR imaging pattern of uncertain significance...

article

Erratum: Relationship between MRI derived right ventricular mass and left ventricular involvement in patients with anderson-fabry disease

Ming-Yen Ng, Qin Li, Anna Calleja, Djeven P Deva, more

Journal of Cardiovascular Magnetic Resonance > 2015 > 17 > 1 > 1-1

article

Utility of coronary CT angiography in outpatients with hypertrophic cardiomyopathy presenting with angina symptoms

Masoud Shariat, Paaladinesh Thavendiranathan, Elsie Nguyen, Bernd Wintersperger, more

Journal of Cardiovascular Computed Tomography > 2014 > 8 > 6 > 429-437

Angina is a frequent symptom in patients with hypertrophic cardiomyopathy (HCM); however, it is often not because of significant epicardial coronary artery stenosis. Coronary CT angiography (CCTA) is an excellent modality to rule out significant coronary artery stenosis in the low- and intermediate-risk patients; however, its value in patients with HCM has not been explored. We sought to assess the...

article

Pilot Study Comparison with Standard Through-plane 2D Phase-contrast Imaging

Kate Hanneman, Milani Sivagnanam, Elsie T. Nguyen, Rachel Wald, more

Academic Radiology > 2014 > 21 > 8 > 1002-1008

To investigate four-dimensional (4D) phase-contrast (PC) magnetic resonance (MR) in the evaluation of intracardiac shunts by simultaneous assessment of pulmonary (Q_P) and systemic (Q_S) flows in a pilot study and to compare results to through-plane two-dimensional (2D) PC MR.Institutional review board approval and written informed consent were obtained. Nineteen patients with suspected intracardiac...

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Search results for: Andrew M. Crean

Cardiac MRI and radionuclide ventriculography for measurement of left ventricular ejection fraction in ICD candidates

Noninvasive hematocrit assessment for cardiovascular magnetic resonance extracellular volume quantification using a point-of-care device and synthetic derivation

Phenotype, management and predictors of outcome in a large cohort of adult congenital heart disease patients with heart failure

The Role of Radionuclide Imaging in Congenital Heart Disease

Patient Selection Process for the Harmony Transcatheter Pulmonary Valve Early Feasibility Study

Harmony Feasibility Trial

Management of Bilateral Axillary Aneurysms, Threatened Limb, and Diffuse Vasculopathy in a Patient With ACTA2 Mutation

Proving the innocence of a “malignant” coronary artery: Calling dobutamine stress CT for the defence!

The IMPACT-CABG trial: A multicenter, randomized clinical trial of CD133+ stem cell therapy during coronary artery bypass grafting for ischemic cardiomyopathy

Uric acid bladder stones in congenital cyanotic heart disease

Does a dedicated subspecialty ACHD coronary clinic result in greater consistency in approach and reduced loss to follow-up? An evaluation of the first 3years of the Toronto Congenital Coronary Clinic for Adults

Endorsed by the Society of Pediatric Radiology (SPR) and the North American Society of Cardiac Imaging (NASCI)

Endorsed by the Society of Pediatric Radiology (SPR) and the North American Society of Cardiac Imaging (NASCI)

Percutaneous Correction of Right Superior Vena Cava to Left Atrium

Outcomes of Aortic Valve-Sparing Operations in Marfan Syndrome

Use of Cardiac Magnetic Resonance Imaging Based Measurements of Inferior Vena Cava Cross-Sectional Area in the Diagnosis of Pericardial Constriction

Significance of Late Gadolinium Enhancement at Right Ventricular Attachment to Ventricular Septum in Patients With Hypertrophic Cardiomyopathy

Erratum: Relationship between MRI derived right ventricular mass and left ventricular involvement in patients with anderson-fabry disease

Utility of coronary CT angiography in outpatients with hypertrophic cardiomyopathy presenting with angina symptoms

Pilot Study Comparison with Standard Through-plane 2D Phase-contrast Imaging

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