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Bacterial lineages that chronically infect cystic fibrosis (CF) patients genetically diversify during infection. However, the mechanisms driving diversification are unknown. By dissecting ten CF lung pairs and studying ∼12,000 regional isolates, we were able to investigate whether clonally related Pseudomonas aeruginosa inhabiting different lung regions evolve independently and differ functionally...
In pathogenic Gram-negative bacteria, interactions among membrane proteins are key mediators of host cell attachment, invasion, pathogenesis, and antibiotic resistance. Membrane protein interactions are highly dependent upon local properties and environment, warranting direct measurements on native protein complex structures as they exist in cells. Here we apply in vivo chemical cross-linking mass...
A wireless sensor networks (WSNs) is typically made up of numerous sensors which have different clock accuracies. Time synchronization is crucial to maintain data consistency, coordination, and perform other fundamental operations: power management, security, and data fusion and scheduling. In order to realize united time, the united time service system or the time server must be established. In this...
Many applications in industrial wireless sensor networks require time synchronization. Time synchronization is required for consistent distributed sensing and industrial control. In order to realize united time, the united time service system or the time server must be established. Based on industrial wireless sensor networks, information fusion automatically analyzes and monitors information under...
Industrial wireless sensor network have emerged as an interesting and important research area in the last few years. Time synchronization is required for consistent distributed sensing and industrial control. In order to realize united time, the united time service system or the time server must be established. Based on industrial wireless sensor networks, information fusion automatically analyzes...
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