Search results for: Rui Dong

Items from 1 to 20 out of 328 results

article

Antigen clearance at the peak of the primary immune response induces experimental autoimmune encephalomyelitis

Peiguo Zheng, Xufeng Wei, Xuezhen Cao, Panhong Ma, more

European Journal of Immunology > 53 > 3 > n/a - n/a

Autoimmune demyelinating diseases can be induced by an immune response against myelin peptides; however, the exact mechanism underlying the development of such diseases remains unclear. In experimental autoimmune encephalomyelitis, we found that the clearance of exogenous myelin antigen at the peak of the primary immune response is key to the pathogenesis of the disease. The generation of effector...

article

Population Pharmacokinetic Modeling Combined With Machine Learning Approach Improved Tacrolimus Trough Concentration Prediction in Chinese Adult Liver Transplant Recipients

Zi‐ran Li, Rui‐dong Li, Wan‐jie Niu, Xin‐yi Zheng, more

The Journal of Clinical Pharmacology > 63 > 3 > 314 - 325

This study aimed to develop and evaluate a population pharmacokinetic (PPK) combined machine learning approach to predict tacrolimus trough concentrations for Chinese adult liver transplant recipients in the early posttransplant period. Tacrolimus trough concentrations were retrospectively collected from routine monitoring records of liver transplant recipients and divided into the training data set...

article

Enhancement of astrocytic gap junctions Connexin43 coupling can improve long‐term isoflurane anesthesia–mediated brain network abnormalities and cognitive impairment

Rui Dong, Pin Lv, Yuqiang Han, Linhao Jiang, more

CNS Neuroscience & Therapeutics > 28 > 12 > 2281 - 2297

Aim Astrocytes are connected by gap junctions Connexin43 (GJs‐Cx43) forming an extensive intercellular network and maintain brain homeostasis. Perioperative neurocognitive disorder (PND) occurs frequently after anesthesia/surgery and worsens patient outcome, but the neural circuit mechanisms remain unclear. This study aimed to determine the effects of the GJs‐Cx43–mediated astrocytic network on PND...

article

An elastic recommender process for cloud service recommendation scalability

Rui‐dong Qi, Jian‐tao Zhou, Zhuowei Wang, Xiaoyu Song

Concurrency and Computation: Practice and Experience > 34 > 21 > n/a - n/a

Cloud computing services are ubiquitous in society and cloud recommender systems play a crucial role in intelligently selecting services for cloud users. Currently, recommendations are static with low scalability. Only one recommendation list is generated at a time and the recommender strategy in the recommendation cycle is not adjustable. This paper presents a new elastic recommender process (ERP)...

article

An experimental/computational study of steric hindrance effects on CO₂ absorption in (non)aqueous amine solutions

Qinlan Luo, Rui Dong, Bohak Yoon, Hongxia Gao, more

AIChE Journal > 68 > 7 > n/a - n/a

The reaction kinetics and molecular mechanisms of CO₂ absorption using nonaqueous and aqueous monoethanolamine (MEA)/methyldiethanolamine (MDEA)/2‐amino‐2‐methy‐1‐propanol (AMP) solutions were analyzed by the stopped‐flow technique and ab initio molecular dynamics (AIMD) simulations. Pseudo first‐order rate constants (k₀) of reactions between CO₂ and amines were measured. A kinetic model was proposed...

article

Introduction of a Cys360Tyr Mutation in ANO5 Creates a Mouse Model for Gnathodiaphyseal Dysplasia

Hongyu Li, Xiaoyu Wang, Erjun Chen, Xiu Liu, more

Journal of Bone and Mineral Research > 37 > 3 > 515 - 530

Gnathodiaphyseal dysplasia (GDD) is a rare autosomal dominant genetic disease characterized by the osteosclerosis of tubular bones and the formation of cemento‐osseous lesions in mandibles. Although genetic mutations for GDD have been identified in the ANO5/TMEM16E gene, the cellular and molecular mechanisms behind the pathogenesis of GDD remain unclear. Here, we generated the first knock‐in mouse...

article

Efficient and Broadband LiGaP₂O₇:Cr³⁺ Phosphors for Smart Near‐Infrared Light‐Emitting Diodes

Chenxu Yuan, Ruiyang Li, Yongfu Liu, Liangliang Zhang, more

Laser & Photonics Reviews > 15 > 11 > n/a - n/a

Broadband near‐infrared (NIR) phosphor‐converted (pc) LED is promising next‐generation tiny light source for smart and broadband NIR spectroscopy technology. However, NIR phosphors suffer from challenges in terms of low quantum efficiency and bandwidth. By selecting a host that has a big bandgap and weakening coupling effect among Cr³⁺, a novel LiGaP₂O₇:Cr³⁺ (LGAP:Cr³⁺) NIR phosphor that has a high...

article

Diversity of fungal isolates from fungus‐growing termite Macrotermes barneyi and characterization of bioactive compound from Xylaria escharoidea

Venkateswarulu Nagam, Rammohan Aluru, Muhammad Shoaib, Guang‐Rui Dong, more

Insect Science > 28 > 2 > 392 - 402

Owing to their potential applications, as well as their structural diversity, the discovery of novel secondary metabolites from insect‐associated fungi has been of interest to researchers in recent years. The aim of this study was therefore to estimate the diversity of fungi associated with fungus‐growing termites and bioprospecting these for potential secondary metabolites. In total, 18 fungal species...

article

Left Hepatic Vein Preferential Approach Based on Anatomy Is Safe and Feasible for Laparoscopic Living Donor Left Lateral Sectionectomy

Lu Lu, Zheng‐Xin Wang, Wen‐Wei Zhu, Cong‐Huan Shen, more

Liver Transplantation > 27 > 1 > 88 - 95

We assess the safety and feasibility of the left hepatic vein preferential approach (LHVPA) based on left hepatic vein (LHV) anatomy for living donor laparoscopic left lateral sectionectomy (LLLS). Data from 50 donors who underwent LLLS in Huashan Hospital from October 2016 to November 2019 were analyzed retrospectively. On the basis of the classification of the LHV anatomy, the vein was defined as...

article

The effect of formalism on unethical decision making: The mediating effect of moral disengagement and moderating effect of moral attentiveness

Rui Dong, Ting Lu, Qiaolong Hu, Shiguang Ni

Business Ethics, the Environment & Responsibility > 30 > 1 > 127 - 142

This study examined the relationship between formalism and unethical decision making among Chinese working adults. A total of 316 Chinese adult employees completed measures of ethical predispositions, unethical decision making, moral disengagement, and moral attentiveness. The results showed that formalism was related to a weaker propensity to morally disengage. Moral disengagement positively predicted...

article

Numerical simulation of the mass transfer process of CO₂ absorption by different solutions in a microchannel

Rui Dong, Di Chu, Qiqi Sun, Zunlong Jin

The Canadian Journal of Chemical Engineering > 98 > 12 > 2648 - 2664

The flow and mass transfer characteristics of CO₂ absorption in different liquid phases in a microchannel were studied by numerical simulation. The mixture gas phase contained 5 vol% CO₂ and 95 vol% N₂, and the different liquid phases were water, ethanol solution, 0.2 M monoethanolamine solution, and 0.2 M NaOH solution, respectively. Based on the permeation theory, the distribution of velocity and...

article

Differential effects of different antipsychotic drugs on cognitive function in patients with chronic schizophrenia

Rui Dong, Lian Yuan, Yong Yang, Xiang‐Dong Du, more

Human Psychopharmacology: Clinical and Experimental > 35 > 6 > 1 - 8

Background Cognitive impairment is core feature of schizophrenia. The impact of antipsychotics on cognition remains controversial. This study aimed to examine the effects of long‐term use of different types of antipsychotics on cognitive impairment in schizophrenia patients. Methods We used the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) to assess the cognition of...

article

Circulating tumor DNA in neuroblastoma

Meng Wei, Mujie Ye, Kuiran Dong, Rui Dong

Pediatric Blood & Cancer > 67 > 10 > n/a - n/a

As a sympathetic nervous system–derived tumor, aggressive neuroblastoma (NB) is currently attracting interest from researchers seeking diagnostic and prognostic markers via less invasive procedures. The analysis of circulating tumor DNA (ctDNA) in peripheral blood can provide genetic information from multiple tumor lesions and is not dependent on a surgical procedure. The identification of genetic...

article

A touching letter vs a terrible tragedy：What we learned

Hong Wang, Rui Dong

International Journal of Clinical Practice > 74 > 8 > n/a - n/a

article

YAG:Ce³⁺ Transparent Ceramic Phosphors Brighten the Next‐Generation Laser‐Driven Lighting

Qi Yao, Pan Hu, Peng Sun, Min Liu, more

Advanced Materials > 32 > 19 > n/a - n/a

Y₃Al₅O₁₂:Ce³⁺ (YAG:Ce³⁺) transparent ceramic phosphors (TCPs) are regarded as the most promising luminescent converter for laser‐driven (LD) lighting. High‐quality YAG:Ce³⁺ TCPs are still urgent for high efficiency LD lighting devices. YAG:Ce³⁺ TCPs in a vacuum ambience by using nano‐sized raw materials are prepared. Controlling defects by adding nano‐sized MgO and SiO₂ simultaneously enables a high...

article

FAM96B inhibits the senescence of dental pulp stem cells

Hanbing Liang, Wenzhi Li, Haoqing Yang, Yangyang Cao, more

Cell Biology International > 44 > 5 > 1193 - 1203

Dental pulp stem cells (DPSCs) are considered a remarkable source for the regeneration of dental pulp tissues, but their therapeutic effectiveness remains limited, especially in elderly people. Previous studies found that senescence has a negative effect on the proliferation and differentiation potential of DPSCs. Moreover, numerous long non‐coding RNA (lncRNA) and messenger RNA were significantly...

article

Gut microbial profile in biliary atresia: a case‐control study

Junfeng Wang, Tian Qian, Jingying Jiang, Yifan Yang, more

Journal of Gastroenterology and Hepatology > 35 > 2 > 334 - 342

Background and Aim Biliary atresia (BA) is a progressive fibro‐inflammatory cholangiopathy with an unclear etiology. Various liver disorders are associated with an altered microbiome. However, gut microbiome in BA remains unknown. Here, we performed a case‐control study to investigate the gut microbiota in BA. Methods A cross‐sectional analysis was first conducted for 34 BA patients and 34 healthy...

article

Carotid artery blood velocity decreases in patients with coronary slow flow: A manifestation of systemic arteriosclerosis

Rui Dong, Qian Lv, Yannan Gao, Caiyun He, more

Echocardiography > 36 > 12 > 2234 - 2240

Objectives Coronary slow flow phenomenon (CSFP) could be a manifestation of systemic arteriosclerosis, as coronary and carotid arteries have similar intimal thickening. However, as an initial cause of arteriosclerosis, hemodynamic changes in carotid arteries have rarely been studied. Methods Twenty patients with angiography‐proven CSFP and 39 patients with normal coronary flow (NCF) were enrolled...

article

Establishment of a human iPSC line (SDQLCHi010-A) from a patient with optic nerve malformation carrying a heterozygous mutation in PAX6 gene

Haiyan Zhang, Yanyan Ma, Shujuan Yu, Xiaomeng Yang, more

Stem Cell Research > 2019 > 41 > C

We established an induced pluripotent stem cell (iPSC) line (SDQLCHi010-A) from peripheral blood mononuclear cells isolated from a 4-year-old boy with optic nerve malformation and intellectual disability carrying a heterozygous mutation (c.220A>G (p.S74G)) in PAX6 gene. Non-integrating episomal vectors containing OCT4, SOX2, KLF4, BCL-XL and MYC were used for reprogramming. The established iPSC...

article

An integration-free iPSC line (SDQLCHi013-A) derived from a patient with maple syrup urine disease carrying compound heterozygote mutations in BCKDHA gene

Haiyan Zhang, Yanyan Ma, Xiaomei Li, Xiaomeng Yang, more

Stem Cell Research > 2019 > 41 > C

The human induced pluripotent stem cell (iPSC) line SDQLCHi013-A was generated from peripheral blood mononuclear cells of a 7-day-old infant, who was diagnosed with maple syrup urine disease and carried compound heterozygote mutations (c.1280_1282 delTGG and c.632C>T) in BCKDHA gene. Non-integrating episomal vectors coding OCT4, SOX2, KLF4, BCL-XL and MYC were used for reprogramming. The established...

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INFONA - science communication portal

Search results for: Rui Dong

Antigen clearance at the peak of the primary immune response induces experimental autoimmune encephalomyelitis

Population Pharmacokinetic Modeling Combined With Machine Learning Approach Improved Tacrolimus Trough Concentration Prediction in Chinese Adult Liver Transplant Recipients

Enhancement of astrocytic gap junctions Connexin43 coupling can improve long‐term isoflurane anesthesia–mediated brain network abnormalities and cognitive impairment

An elastic recommender process for cloud service recommendation scalability

An experimental/computational study of steric hindrance effects on CO₂ absorption in (non)aqueous amine solutions

Introduction of a Cys360Tyr Mutation in ANO5 Creates a Mouse Model for Gnathodiaphyseal Dysplasia

Efficient and Broadband LiGaP₂O₇:Cr³⁺ Phosphors for Smart Near‐Infrared Light‐Emitting Diodes

Diversity of fungal isolates from fungus‐growing termite Macrotermes barneyi and characterization of bioactive compound from Xylaria escharoidea

Left Hepatic Vein Preferential Approach Based on Anatomy Is Safe and Feasible for Laparoscopic Living Donor Left Lateral Sectionectomy

The effect of formalism on unethical decision making: The mediating effect of moral disengagement and moderating effect of moral attentiveness

Numerical simulation of the mass transfer process of CO₂ absorption by different solutions in a microchannel

Differential effects of different antipsychotic drugs on cognitive function in patients with chronic schizophrenia

Circulating tumor DNA in neuroblastoma

A touching letter vs a terrible tragedy：What we learned

YAG:Ce³⁺ Transparent Ceramic Phosphors Brighten the Next‐Generation Laser‐Driven Lighting

FAM96B inhibits the senescence of dental pulp stem cells

Gut microbial profile in biliary atresia: a case‐control study

Carotid artery blood velocity decreases in patients with coronary slow flow: A manifestation of systemic arteriosclerosis

Establishment of a human iPSC line (SDQLCHi010-A) from a patient with optic nerve malformation carrying a heterozygous mutation in PAX6 gene

An integration-free iPSC line (SDQLCHi013-A) derived from a patient with maple syrup urine disease carrying compound heterozygote mutations in BCKDHA gene

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