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A series of 2-methoxyphenyl piperazine analogues containing a triazole ring were synthesized and their in vitro binding affinities at human dopamine D 2 and D 3 receptors were evaluated. Compounds 5b, 5c, 5d, and 4g, demonstrate high affinity for dopamine D 3 receptors and moderate selectivity for the dopamine D 3 versus D 2 receptor subtypes. To further examine...
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