The class I myosin, Myo1b, is a calmodulin- and actin-associated molecular motor widely expressed in mammalian tissues. Analytical ultracentrifugation studies indicate that Myo1b purified from rat liver has a Stokes radius of 6.7nm and a sedimentation coefficient, s20,w, of 7.0 S with a predicted molar mass of 213kg/mol. These results indicate that Myo1b is monomeric and consists primarily of a splice...
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