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Introduction
Thoracoabdominal normothermic regional perfusion (TA‐NRP) following cardiac death is an emerging multivisceral organ procurement technique. Recent national studies on outcomes of presumptive TA‐NRP‐procured organs are limited by potential misclassification since TA‐NRP is not differentiated from donation after cardiac death (DCD) in registry data.
Methods
We studied 22 donors whose...
Intragraft events thought to be relevant to the development of tolerance are here subjected to a comprehensive mechanistic study during long‐term spontaneous tolerance that occurs in C57BL/6 mice that receive life sustaining DBA/2 kidneys. These allografts rapidly develop periarterial Treg‐rich organized lymphoid structures (TOLS) that form in response to class II but not to class I MHC disparity...
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