Search results for: Lisa Taylor

Items from 1 to 20 out of 33 results

article

Associations between neuropsychiatric symptoms of affective and vegetative domains and brain morphology in aging people with mild cognitive impairment and Alzheimer's disease

Adriana Cannizzaro, Lucas Ronat, Lyna Mariam El Haffaf, Alexandru Hanganu, more

International Journal of Geriatric Psychiatry > 38 > 6 > n/a - n/a

Objective Neuropsychiatric symptoms (NPS) are common in mild cognitive impairment (MCI) and even more in Alzheimer's disease (AD). The symptom‐based cluster including nighttime disturbances, depression, appetite changes, anxiety, and apathy (affective and vegetative symptoms) was associated with an increased risk of dementia in MCI and has common neuroanatomical associations. Our objective was to...

article

Tau‐Atrophy Variability Reveals Phenotypic Heterogeneity in Alzheimer's Disease

Sandhitsu R. Das, Xueying Lyu, Michael Tran Duong, Long Xie, more

Annals of Neurology > 90 > 5 > 751 - 762

Objective Tau neurofibrillary tangles (T) are the primary driver of downstream neurodegeneration (N) and subsequent cognitive impairment in Alzheimer's disease (AD). However, there is substantial variability in the T‐N relationship – manifested in higher or lower atrophy than expected for level of tau in a given brain region. The goal of this study was to determine if region‐based quantitation of...

article

Adding evidence to the role of NEUROG1 in congenital cranial dysinnervation disorders

Juliette Dupont, José Pedro Vieira, Ana Lisa Taylor Tavares, Carla Ribeiro Conceição, more

Clinical Genetics > 99 > 4 > 588 - 593

Congenital cranial dysinnervation disorders (CCDDs) are a heterogeneous group of neurodevelopmental phenotypes caused by a primary disturbance of innervation due to deficient, absent, or misguided cranial nerves. Although some CCDDs genes are known, several clinical phenotypes and their aetiologies remain to be elucidated. We describe a 12‐year‐old boy with hypotonia, developmental delay, sensorineural...

article

Maternity Care for Pregnant Women with Opioid Use Disorder: A Review

Abigail H. Rizk, Sara E. Simonsen, Leissa Roberts, Lisa Taylor‐Swanson, more

Journal of Midwifery & Women's Health > 64 > 5 > 532 - 544

Opioid misuse is a problem that is complex and widespread. Opioid misuse rates are rising across all US demographics, including among pregnant women. The opioid epidemic brings a unique set of challenges for maternity health care providers, ranging from ethical considerations to the complex health needs and risks for both woman and fetus. This article addresses care for pregnant women during the antepartum,...

article

The influence of electrostatic properties on the punch sticking propensity of pharmaceutical blends

Leila Samiei, Karen Kelly, Lisa Taylor, Ben Forbes, more

Powder Technology > 2017 > 305 > C > 509-517

The present study details characterisation of the electrostatic properties of a range of active pharmaceutical ingredients (APIs) and blends and investigates the role of electrostatics as a potential root cause of punch sticking during tabletting.Microcrystalline cellulose (AVICEL® PH-102) and magnesium stearate were used to prepare blends of constant drug loading (10% w/w) with a range of APIs. The...

chapter

A Novel Transfer Learning Method Based on Common Space Mapping and Weighted Domain Matching

Ru-Ze Liang, Wei Xie, Weizhi Li, Hongqi Wang, more

2016 IEEE 28th International Conference on Tools with Artificial Intelligence (ICTAI) > 299 - 303

2016 IEEE 28th International Conference on Tools with Artificial Intelligence (ICTAI)

In this paper, we propose a novel learning framework for the problem of domain transfer learning. We map the data of two domains to one single common space, and learn a classifier in this common space. Then we adapt the common classifier to the two domains by adding two adaptive functions to it respectively. In the common space, the target domain data points are weighted and matched to the target...

article

Don't go with the ‘FLO’ – a student mobile texting service to enhance nursing student retention

Elizabeth Boath, Annette Jinks, Nigel Thomas, Roy Thompson, more

Nurse Education Today > 2016 > 45 > C > 80-86

The review undertaken revealed that there is an abundance of literature concerning retention and the high levels of attrition among undergraduate students and of relevance here, nurse education. The study undertaken evaluated the use of mobile phone automated texts designed to provide information, support and reassurance to help alleviate the stress and anxieties that some undergraduate nursing students...

article

Using an interlaboratory study to revise methods for conducting 10‐d to 42‐d water or sediment toxicity tests with Hyalella azteca

Chris D. Ivey, Chris G. Ingersoll, William G. Brumbaugh, Edward J. Hammer, more

Environmental Toxicology and Chemistry > 35 > 10 > 2439 - 2447

Studies have been conducted to refine US Environmental Protection Agency, ASTM International, and Environment Canada standard methods for conducting 42‐d reproduction tests with Hyalella azteca in water or in sediment. Modifications to the H. azteca method include better‐defined ionic composition requirements for exposure water (i.e., >15 mg/L of chloride and >0.02 mg/L of bromide) and improved...

article

Effects of isoflavones and amino acid therapies for hot flashes and co-occurring symptoms during the menopausal transition and early postmenopause: A systematic review

Annette J. Thomas, Rita Ismail, Lisa Taylor-Swanson, Lori Cray, more

Maturitas > 2014 > 78 > 4 > 263-276

Review controlled clinical trials of isoflavones and amino acid preparation effects on hot flashes and at least one other symptom including mood, sleep, pain, and cognitive function that women report during the menopausal transition and early postmenopause.An experienced reference librarian searched PubMed/Medline, CINAHL Plus, PsycInfo, Cochrane Database of Systematic Reviews, Cochrane Central Register...

article

The characteristics of particulate absorption, scattering and attenuation coefficients in the surface ocean; Contribution of the Tara Oceans expedition

Emmanuel Boss, Marc Picheral, Thomas Leeuw, Alison Chase, more

Methods in Oceanography > 2013 > 7 > Complete > 52-62

A dataset consisting of AC-S measurements of (hyper-) spectral particulate absorption, scattering and attenuation coefficients were obtained from measurements performed on the flow-through system of the R/V Tara during its 2.5-year long expedition.The AC-S instruments were robust, working continuously with weekly maintenance for about 3 months at a time, and provided absorption (attenuation) data...

article

The levels of water-soluble and triton-soluble Aβ are increased in Alzheimer's disease brain

Jessica M. McDonald, Nigel J. Cairns, Lisa Taylor-Reinwald, David Holtzman, more

Brain Research > 2012 > 1450 > Complete > 138-147

Although plaques composed of the amyloid β-protein (Aβ) are considered a defining feature of Alzheimer's disease (AD), they are also found in cognitively normal individuals and extensive evidence suggests that non-plaque, water-soluble forms of Aβ may play a role in AD pathogenesis. However, the relationship between the levels of water-soluble Aβ and the clinical severity of disease has never been...

article

Neuropathology of preclinical and incipient Alzheimer's dementia

Lisa Taylor-Reinwald, Elizabeth Grant, Alison Goate, John Morris, more

Alzheimer's & Dementia: The Journal of the Alzheimer's Association > 2011 > 7 > 4 Supplement > S303

article

Neuropathologic assessment of ADNI participants: The essential role of the neuropathology core

Nigel Cairns, Lisa Taylor-Reinwald, John Morris

Alzheimer's & Dementia: The Journal of the Alzheimer's Association > 2011 > 7 > 4 Supplement > S699

article

Thermometer of warmth in the patient–provider relationship (WARMOMETER) Theory-based development of a patient self-report measure and initial validation using cognitive interview methodology

Melanie Neumann, Christian Scheffer, Dirk Cysarz, Maxie Bovelet, more

Patient Education and Counseling > 2011 > 82 > 3 > 361-369

The aims of this study are twofold: (1) the theory-based development of a patient self-report measure of physician warmth and (2) the application of cognitive interview methodology to understand patients’ perception and interpretation of this new measure.A draft measure was developed based on an in-depth literature review of the concept of human warmth by a multidisciplinary expert group. Sixteen...

article

Nitrogen fixation potential in global chickpea mini-core collection

Abbas Biabani, Lynne Carpenter-Boggs, Clarice J. Coyne, Lisa Taylor, more

Biology and Fertility of Soils > 2011 > 47 > 6 > 679-685

Biological nitrogen fixation (BNF) is a sustainable alternative for nitrogen supply to agriculture worldwide. One approach to increasing BNF in agriculture is to breed and use legumes with greater BNF capacity. To assess the capacity for BNF in chickpea (Cicer arietinum) global germplasm, a genetically diverse subset from the USDA global chickpea core collection was assayed for BNF potential. The...

article

Characterization of a unique IgG1 mAb CEX profile by limited Lys-C proteolysis/CEX separation coupled with mass spectrometry and structural analysis

Jaewon Kim, Laurie Jones, Lisa Taylor, Gunasekaran Kannan, more

Journal of Chromatography B > 2010 > 878 > 22 > 1973-1981

The unique cation exchange chromatography (CEX) charge variant profile of mAb1 is characterized by a combination of mass spectrometry, limited Lys-C digestion followed by CEX separation and structural analysis. During CEX method development, mAb1 showed several unexpected phenomena, including a unique profile containing two main species (acidic 2 and main) and significant instability during stability...

article

TDP-43 proteinopathy in cognitively normal (CDR 0) individuals

Lisa Taylor-Reinwald, Elizabeth Grant, John C. Morris, Nigel J. Cairns

Alzheimer's & Dementia > 2010 > 6 > 4(S) > S84

article

Autopsy consent, brain collection, and standardized neuropathologic assessment of ADNI participants: The essential role of the Neuropathology Core

Nigel J. Cairns, Lisa Taylor-Reinwald, John C. Morris

Alzheimer's & Dementia: The Journal of the Alzheimer's Association > 2010 > 6 > 3 > 274-279

Our objectives are to facilitate autopsy consent, brain collection, and perform standardized neuropathologic assessments of all Alzheimer's Disease Neuroimaging Initiative (ADNI) participants who come to autopsy at the 58 ADNI sites in the USA and Canada.Building on the expertise and resources of the existing Alzheimer's Disease Research Center (ADRC) at Washington University School of Medicine, St...

article

Prophylactic administration of avotermin for improvement of skin scarring: three double-blind, placebo-controlled, phase I/II studies

Mark WJ Ferguson, Jonathan Duncan, Jeremy Bond, James Bush, more

The Lancet > 2009 > 373 > 9671 > 1264-1274

Research into mechanisms of skin scarring identified transforming growth factor β3 (TGFβ3) as a potential antiscarring therapy. We assessed scar improvement with avotermin (recombinant, active, human TGFβ3). In three double-blind, placebo-controlled studies, intradermal avotermin (concentrations ranging from 0·25 to 500 ng/100 μL per linear cm wound margin) was administered to both margins of 1...

article

3. Hanging toy versus rootable toy of the same material

Kamara Scott, Lisa Taylor, Bhupinder Pal Gill, Sandra A. Edwards

Applied Animal Behaviour Science > 2009 > 116 > 2-4 > 186-190

This study aimed to assess the effects of (1) environmental enrichment with either straw bedding or a plastic toy and (2) the way in which the plastic toy was presented on the behaviour of finishing pigs in two different housing systems. One thousand and twenty four (Large White×Landrace)×Large White pigs were housed contemporarily in either a straw-based (ST) or fully slatted (FS) building from 35kg...

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INFONA - science communication portal

Search results for: Lisa Taylor

Associations between neuropsychiatric symptoms of affective and vegetative domains and brain morphology in aging people with mild cognitive impairment and Alzheimer's disease

Tau‐Atrophy Variability Reveals Phenotypic Heterogeneity in Alzheimer's Disease

Adding evidence to the role of NEUROG1 in congenital cranial dysinnervation disorders

Maternity Care for Pregnant Women with Opioid Use Disorder: A Review

The influence of electrostatic properties on the punch sticking propensity of pharmaceutical blends

A Novel Transfer Learning Method Based on Common Space Mapping and Weighted Domain Matching

Don't go with the ‘FLO’ – a student mobile texting service to enhance nursing student retention

Using an interlaboratory study to revise methods for conducting 10‐d to 42‐d water or sediment toxicity tests with Hyalella azteca

Effects of isoflavones and amino acid therapies for hot flashes and co-occurring symptoms during the menopausal transition and early postmenopause: A systematic review

The characteristics of particulate absorption, scattering and attenuation coefficients in the surface ocean; Contribution of the Tara Oceans expedition

The levels of water-soluble and triton-soluble Aβ are increased in Alzheimer's disease brain

Neuropathology of preclinical and incipient Alzheimer's dementia

Neuropathologic assessment of ADNI participants: The essential role of the neuropathology core

Thermometer of warmth in the patient–provider relationship (WARMOMETER) Theory-based development of a patient self-report measure and initial validation using cognitive interview methodology

Nitrogen fixation potential in global chickpea mini-core collection

Characterization of a unique IgG1 mAb CEX profile by limited Lys-C proteolysis/CEX separation coupled with mass spectrometry and structural analysis

TDP-43 proteinopathy in cognitively normal (CDR 0) individuals

Autopsy consent, brain collection, and standardized neuropathologic assessment of ADNI participants: The essential role of the Neuropathology Core

Prophylactic administration of avotermin for improvement of skin scarring: three double-blind, placebo-controlled, phase I/II studies

3. Hanging toy versus rootable toy of the same material

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