Search results for: Khaled Taha-Abdelaziz

Items from 1 to 7 out of 7 results

article

Characterizaton of gamma delta T cells in Marek’s disease virus (Gallid herpesvirus 2) infection of chickens

Adrianna M.S. Laursen, Raveendra R. Kulkarni, Khaled Taha-Abdelaziz, Brandon L. Plattner, more

Virology > 2018 > 522 > C > 56-64

Immunity against Marek's disease (MD), caused by Gallid herpesvirus 2 (GaHV-2), in chickens is mediated by both innate and adaptive responses. The present study evaluated the effects of GaHV-2 infection on distribution and frequency of γδ T cells in tissues, as well as their expression of cytokines. We found that the infected chickens had significantly higher number of γδ T cells in their spleens...

article

Induction of immune response in chickens primed in ovo with an inactivated H9N2 avian influenza virus vaccine

Jake Astill, Tamiru Alkie, Alexander Yitbarek, Khaled Taha-Abdelaziz, more

BMC Research Notes > 2018 > 11 > 1 > 1-7

Objective Infection of chickens with low pathogenic avian influenza virus, such as H9N2 virus, culminates in decreased egg production and increased mortality and morbidity if co-infection with other respiratory pathogens occurs. We have previously observed the induction of antibody- and cell-mediated immune responses after intramuscular administration of an H9N2 beta-propiolactone inactivated virus...

article

Oral administration of PLGA-encapsulated CpG ODN and Campylobacter jejuni lysate reduces cecal colonization by Campylobacter jejuni in chickens

Khaled Taha-Abdelaziz, Douglas C. Hodgins, Tamiru Negash Alkie, Wanderely Quinteiro-Filho, more

Vaccine > 2018 > 36 > 3 > 388-394

Campylobacter jejuni (C. jejuni) is a major cause of bacterial food-borne illness in humans. It is considered a commensal organism of the chicken gut and infected chickens serve as a reservoir and shed bacteria throughout their lifespan. Contaminated poultry products are considered the major source of infection in humans. Therefore, to reduce the risk of human campylobacteriosis, it is essential to...

article

Gene expression profiling of chicken cecal tonsils and ileum following oral exposure to soluble and PLGA-encapsulated CpG ODN, and lysate of Campylobacter jejuni

Khaled Taha-Abdelaziz, Tamiru Negash Alkie, Douglas C. Hodgins, Alexander Yitbarek, more

Veterinary Microbiology > 2017 > 212 > C > 67-74

Campylobacter jejuni (C. jejuni) is a leading bacterial cause of food-borne illness in humans. Contaminated chicken meat is an important source of infection for humans. Chickens are not clinically affected by colonization, and immune responses following natural infection have limited effects on bacterial load in the gut. Induction of intestinal immune responses may possibly lead to a breakdown of...

article

Characterization of host responses induced by Toll-like receptor ligands in chicken cecal tonsil cells

Khaled Taha-abdelaziz, Tamiru Negash Alkie, Douglas C. Hodgins, Bahram Shojadoost, more

Veterinary Immunology and Immunopathology > 2016 > 174 > C > 19-25

The innate responses of cecal tonsils against invading microorganisms are mediated by conserved pattern recognition receptors (PRRs) such as the Toll-like receptors (TLRs). TLRs expressed by mammalian and avian immune system cells have the capability to recognize pathogen-associated molecular patterns (PAMPs). Although, the role of TLR ligands in innate and adaptive responses in chickens has been...

article

Regulation of tracheal antimicrobial peptide gene expression in airway epithelial cells of cattle

Khaled Taha-Abdelaziz, Leanna Wyer, Lesley Berghuis, Laura L. Bassel, more

Veterinary Research > 2016 > 47 > 1 > 1-7

β-defensins are an important element of the mucosal innate immune response against bacterial pathogens. Tracheal antimicrobial peptide (TAP) has microbicidal activity against the bacteria that cause bovine respiratory disease, and its expression in tracheal epithelial cells is upregulated by bacterial products including lipopolysaccharide (LPS, a TLR4 agonist), Pam3CSK4 (an agonist of Toll-like receptor...

article

Bactericidal activity of tracheal antimicrobial peptide against respiratory pathogens of cattle

Khaled Taha-Abdelaziz, José Perez-Casal, Courtney Schott, Jason Hsiao, more

Veterinary Immunology and Immunopathology > 2013 > 152 > 3-4 > 289-294

Tracheal antimicrobial peptide (TAP) is a β-defensin produced by mucosal epithelial cells of cattle. Although effective against several human pathogens, the activity of this bovine peptide against the bacterial pathogens that cause bovine respiratory disease have not been reported. This study compared the antibacterial effects of synthetic TAP against Mannheimia haemolytica, Histophilus somni, Pasteurella...

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Search results for: Khaled Taha-Abdelaziz

Characterizaton of gamma delta T cells in Marek’s disease virus (Gallid herpesvirus 2) infection of chickens

Induction of immune response in chickens primed in ovo with an inactivated H9N2 avian influenza virus vaccine

Oral administration of PLGA-encapsulated CpG ODN and Campylobacter jejuni lysate reduces cecal colonization by Campylobacter jejuni in chickens

Gene expression profiling of chicken cecal tonsils and ileum following oral exposure to soluble and PLGA-encapsulated CpG ODN, and lysate of Campylobacter jejuni

Characterization of host responses induced by Toll-like receptor ligands in chicken cecal tonsil cells

Regulation of tracheal antimicrobial peptide gene expression in airway epithelial cells of cattle

Bactericidal activity of tracheal antimicrobial peptide against respiratory pathogens of cattle

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