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The Zhacang geothermal field in the Guide Basin, in the northeast of the Tibetan Plateau, is considered a potential target for establishing a geothermal power plant. This study investigated the formation mechanisms of geothermal resources in this field by combining isotopic analysis (3H, D, 18O, 3He and 4He) and numerical modeling of fluid-heat-helium transport. δD and δ18O indicated that the meteoric...