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The effect of opioid analgesia on tests of muscular function in chronic low back pain (CLBP) is unknown. Twenty-eight subjects with CLBP of at least moderate intensity performed the Sorensen isokinetic exercise test once after receiving 1 μg/kg fentanyl intravenously and once after placebo in a randomized-order double-blind crossover design. Naloxone 3 μg/kg was administered after the fentanyl phase...
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