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Amyotrophic lateral sclerosis (ALS) is a lethal neurodegenerative disease, which selectively affects motor neurons throughout the central nervous system. The extensive distribution of motor neurons is an obstacle to applying cell transplantation therapy for the treatment of ALS. To overcome this problem, we developed a cell transplantation method via the fourth cerebral ventricle in mice. We used...
Hintergrund Zur Diagnostik von Riechstörungen ist die morphologische und immunhistochemische Untersuchung der Riechschleimhaut eine zusätzliche Option. Material/Methoden In einer Pilotstudie wurden bei 5 Patienten mit Anosmie nach Schädel-Hirn-Trauma Biopsien des Riechepithels in lokaler Betäubung gewonnen. Das olfaktorische Epithel einer normosmischen Patientin diente als Vergleichsprobe. Die Gefrierschnitte...
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