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Das Neuroblastom ist ein embryonaler Tumor des Kindesalters. Primärtumoren liegen fast ausschließlich retroperitoneal oder abdominal. Neuroblastome produzieren Katecholamine, die als Tumormarker genutzt werden. Die MIBG-Tumorszintigraphie erlaubt neben Sonographie/Magnetresonanztomographie eine spezifische Tumordarstellung. Bei jungen Patienten werden nicht selten Spontanregressionen beobachtet, während...
During the last two decades new diagnostic and therapeutic tools have been utilized to improve the poor survival chances of children with stage 4 neuroblastoma. This study reviews the risk profiles and the long-term outcome of patients from five consecutive German neuroblastoma trials.A total of 96% of all German patients registered at the German childhood cancer registry with neuroblastoma stage...
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