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MicroRNAs (miRNAs) regulate gene expression by inhibiting translation or targeting messenger RNA (mRNA) for degradation in a posttranscriptional fashion. In this study, we show that ectopic expression of miR-34a-5p reduces the mRNA and protein levels of Krüppel-like factor 4 (KLF4). We also demonstrate that miR-34a targets the 3′-untranslated mRNA region of KLF4 and show that overexpression of miR-34a...
Recessive genic male sterility (RGMS) is an important approach to utilize heterosis, but the molecular mechanism of RGMS is not well understood in Sesamum indicum L. 95ms-5AB is a novel male sterility two-type line, which is controlled by a single RGMS gene. Histological observations revealed that abnormal inhibited male gametogenesis appeared during the mononuclear microspore stage. It was characterized...
Hypoxia is well known to occur in contaminated water environments, but it is still unclear about its effects on transcription of hypoxia-inducible genes and apoptotic control genes in zebrafish during development. In this study, the expression of select genes during zebrafish embryonic development was detected at mRNA level to investigate spatio-temporal changes of hypoxia-inducible genes and apoptosis...
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