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In this brief communication, we investigate the role of DEFB103 gene copy number variation (CNV) in ankylosing spondylitis (AS) susceptibility. A total of 807 Chinese individuals including 406 AS patients and 401 controls were enrolled. The DEFB103 copy number was measured by two sets of probes to obtain a stable result in a custom‐by‐design Multiplex AccuCopy™ kit (Genesky Biotechnologies Inc., Shanghai,...
Type 1 diabetes (T1D) is an organ‐specific, T‐cell‐mediated disease resulting from the selective destruction of pancreatic β cells. The signal transducer and activator of transcription 4 (STAT4) gene is one of the most interesting genes for the pathogenesis of autoimmune diseases, including T1D. In this study, a case–control study was conducted in a Han population in northeastern China comparing the...
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