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Geschichtete, mit Protease‐responsiven Peptid‐Biomarkern funktionalisierte und mit siRNA beladene Nanopartikel ermöglichen die nicht‐invasive Harn‐Diagnostik in Mausmodellen drei verschiedener Krebsarten mit gleichzeitiger Genstummschaltung in angrenzenden und metastatischen Mausmodellen von Eierstockkrebs. P. T. Hammond et al. beschreiben in ihrem Forschungsartikel auf S. 2798 eine modulare Nanotheranostik‐Plattform,...
Layer‐by‐layer nanoparticles (NPs) are modular drug delivery vehicles that incorporate multiple functional materials through sequential deposition of polyelectrolytes onto charged nanoparticle cores. Herein, we combined the multicomponent features and tumor targeting capabilities of layer‐by‐layer assembly with functional biosensing peptides to create a new class of nanotheranostics. These NPs encapsulate...
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