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BACKGROUND
Anti‐E is the most common and important RBC alloantibody in the Chinese population. Several studies have demonstrated that the production of specific RBC alloantibodies is associated with HLA‐DRB1 polymorphisms. Considering that the Chinese population has its own unique characteristics of HLA‐DRB1 polymorphisms, we investigate whether specific HLA‐DRB1 alleles are associated with E immunization...
BACKGROUND: Rhnull is a rare autosomal recessive disorder, and Rhnull of the regulator type may result from mutation of the RHAG gene, which encodes RhAG glycoprotein and modulates Rh antigen expression. This study described the molecular genetic analysis of a Chinese Rhnull family and identified a novel mutation in the RHAG gene.
STUDY DESIGN AND METHODS: RBCs from the Rhnull family members were...
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