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Regulatory subsets of B cells (Bregs) modulate immune responses in autoimmunity, cancer, and other inflammation diseases. In the present study, we investigated the numbers of circulating Breg cells in patients with rheumatoid arthritis (RA). We evaluated 59 RA patients and 25 healthy controls. CD19+CD5+CD1dhi B cells and granzyme B-secreting B cells (CD19+CD5+GzmB+) were analyzed by flow cytometry...
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