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A key step of denitrification, the reduction of toxic nitric oxide to nitrous oxide, is catalysed by cytochrome c‐dependent NO reductase (cNOR). cNOR contains four redox‐active cofactors: three hemes and a nonheme iron (FeB). Heme b3 and FeB constitute the active site, but the specific mechanism of NO‐binding events and reduction is under debate. Here, we used a recently constructed, fully folded...
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