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Fibronectin (FN) matrix fibrils assembled in cell culture have been observed to stretch in response to cell movements, and when broken relax to 1/3 to 1/4 of their rest length. Two molecular mechanisms have been proposed for the elasticity. One proposes that FN molecules in relaxed fibers are bent and looped into a compact conformation, and stretching pulls the molecules into the extended conformation...
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